RecName: Full=E3 ubiquitin-protein ligase CBL; AltName: Full=Casitas B - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

Somatic CBL mutation presenting as juvenile myelomonocytic leukemia with vasculitis. [Pediatr Blood Cancer. 2023]
Somatic CBL mutation presenting as juvenile myelomonocytic leukemia with vasculitis.
Mishra V, Krishnan VP, Desai M, Manek H, Pandrowala A, Bodhanwala M, Hiwarkar P. Pediatr Blood Cancer. 2023 Jun; 70(6):e30252. Epub 2023 Feb 14.
Morphologic and Immunophenotypic Differences in Juvenile Myelomonocytic Leukemias With CBL and Other Canonical RAS-pathway Gene Mutations: A Single Institutional Experience. [J Pediatr Hematol Oncol. 2021]
Morphologic and Immunophenotypic Differences in Juvenile Myelomonocytic Leukemias With CBL and Other Canonical RAS-pathway Gene Mutations: A Single Institutional Experience.
Mariani RA, Jennings L, Zhang S, Bhat R, Gong S. J Pediatr Hematol Oncol. 2021 Aug 1; 43(6):e819-e825.
A novel, germline, deactivating CBL variant p.L493F alters domain orientation and is associated with multiple childhood cancers. [Cancer Genet. 2021]
A novel, germline, deactivating CBL variant p.L493F alters domain orientation and is associated with multiple childhood cancers.
Norris GA, Tsai AC, Schneider KW, Wu YH, Caulfield T, Green AL. Cancer Genet. 2021 Jun; 254-255:18-24. Epub 2021 Jan 20.

RefSeq genomic sequence
See the genomic reference sequence for the CBL gene (NG_016808.1).
RefSeq protein
See the reference protein sequence for E3 ubiquitin-protein ligase CBL (NP_005179.2).

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=E3 ubiquitin-protein ligase CBL; AltName: Full=Casitas B-lineage l...
RecName: Full=E3 ubiquitin-protein ligase CBL; AltName: Full=Casitas B-lineage lymphoma proto-oncogene; AltName: Full=Proto-oncogene c-Cbl; AltName: Full=RING finger protein 55; AltName: Full=RING-type E3 ubiquitin transferase CBL; AltName: Full=Signal transduction protein CBL
gi|251757253|sp|P22681.2|CBL_HUMAN

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein