LOCUS 3EU9_B 240 aa linear PRI 27-DEC-2023
DEFINITION Chain B, Huntingtin-interacting protein 14.
ACCESSION 3EU9_B
VERSION 3EU9_B
DBSOURCE pdb: molecule 3EU9, chain B, release Dec 27, 2023;
deposition: Oct 9, 2008;
class: protein binding, methyl-lysine-binding protein;
source: Mmdb_id: 73817, Pdb_id 1: 3EU9;
Exp. method: X-ray Diffraction.
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (residues 1 to 240)
AUTHORS Gao,T., Collins,R.E., Horton,J.R., Zhang,X., Zhang,R., Dhayalan,A.,
Tamas,R., Jeltsch,A. and Cheng,X.
TITLE The ankyrin repeat domain of Huntingtin interacting protein 14
contains a surface aromatic cage, a potential site for
methyl-lysine binding
JOURNAL Proteins 76, 772 (2009)
REFERENCE 2 (residues 1 to 240)
AUTHORS Gao,T., Collins,R.E., Horton,J.R., Zhang,R., Zhang,X. and Cheng,X.
TITLE Direct Submission
JOURNAL Submitted (09-OCT-2008)
COMMENT The ankyrin repeat domain of Huntingtin interacting protein 14.
FEATURES Location/Qualifiers
source 1..240
/organism="Homo sapiens"
/db_xref="taxon:9606"
Region 1..111
/region_name="Domain 3"
/note="NCBI Domains"
SecStr 12..20
/sec_str_type="helix"
/note="helix 15"
Site order(18..20,22..23,27,30,39,41,43,47..48,51..53,55..56,
60,63,72,74,76,81..82,85..87,89..90,94,97,106)
/site_type="other"
/note="oligomer interface [polypeptide binding]"
/db_xref="CDD:293786"
SecStr 22..31
/sec_str_type="helix"
/note="helix 16"
Region 39..240
/region_name="ANKYR"
/note="Ankyrin repeat [Signal transduction mechanisms];
COG0666"
/db_xref="CDD:440430"
Region 41..72
/region_name="ANK repeat"
/note="ANK repeat [structural motif]"
/db_xref="CDD:293786"
SecStr 45..52
/sec_str_type="helix"
/note="helix 17"
SecStr 55..64
/sec_str_type="helix"
/note="helix 18"
SecStr 70..73
/sec_str_type="sheet"
/note="strand 7"
Region 74..106
/region_name="ANK repeat"
/note="ANK repeat [structural motif]"
/db_xref="CDD:293786"
SecStr 75..78
/sec_str_type="sheet"
/note="strand 8"
SecStr 79..86
/sec_str_type="helix"
/note="helix 19"
SecStr 89..98
/sec_str_type="helix"
/note="helix 20"
SecStr 103..107
/sec_str_type="sheet"
/note="strand 9"
Site order(108,110,114..115,118..120,122..123,127,130,139,141,
143,147..148,151..153,156..157,161,164,173,176,178,
182..183,186..188,190..191,195,198,207)
/site_type="other"
/note="oligomer interface [polypeptide binding]"
/db_xref="CDD:293786"
Region 108..139
/region_name="ANK repeat"
/note="ANK repeat [structural motif]"
/db_xref="CDD:293786"
SecStr 108..111
/sec_str_type="sheet"
/note="strand 10"
Region 112..240
/region_name="Domain 4"
/note="NCBI Domains"
SecStr 112..119
/sec_str_type="helix"
/note="helix 21"
SecStr 122..131
/sec_str_type="helix"
/note="helix 22"
Region 141..173
/region_name="ANK repeat"
/note="ANK repeat [structural motif]"
/db_xref="CDD:293786"
SecStr 144..152
/sec_str_type="helix"
/note="helix 23"
SecStr 158..165
/sec_str_type="helix"
/note="helix 24"
SecStr 171..174
/sec_str_type="sheet"
/note="strand 11"
Region 176..207
/region_name="ANK repeat"
/note="ANK repeat [structural motif]"
/db_xref="CDD:293786"
SecStr 176..179
/sec_str_type="sheet"
/note="strand 12"
SecStr 180..187
/sec_str_type="helix"
/note="helix 25"
SecStr 190..199
/sec_str_type="helix"
/note="helix 26"
SecStr 213..221
/sec_str_type="helix"
/note="helix 27"
SecStr 223..230
/sec_str_type="helix"
/note="helix 28"
ORIGIN
1 hmthiddyst wdivkatqyg iyercrelve agydvrqpdk envtllhwaa innridlvky
61 yiskgaivdq lggdlnstpl hwatrqghls mvvqlmkyga dpslidgegc scihlaaqfg
121 htsivaylia kgqdvdmmdq ngmtplmwaa yrthsvdptr llltfnvsvn lgdkyhknta
181 lhwavlagnt tvisllleag anvdaqnikg esaldlakqr knvwminhlq earqakgydn
//