U.S. flag

An official website of the United States government

Chain D, Metal homeostasis factor ATX1

PDB: 3K7R_D

Identical Proteins FASTA Graphics 

LOCUS       3K7R_D                    73 aa            linear   PLN 06-SEP-2023
DEFINITION  Chain D, Metal homeostasis factor ATX1.
ACCESSION   3K7R_D
VERSION     3K7R_D
DBSOURCE    pdb: molecule 3K7R, chain D, release Sep 6, 2023;
            deposition: Oct 13, 2009;
            class: CHAPERONE;
            source: Mmdb_id: 78338, Pdb_id 1: 3K7R;
            Exp. method: X-ray Diffraction.
KEYWORDS    .
SOURCE      Saccharomyces cerevisiae (brewer's yeast)
  ORGANISM  Saccharomyces cerevisiae
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (residues 1 to 73)
  AUTHORS   Alvarez,H.M., Xue,Y., Robinson,C.D., Canalizo-Hernández,M.A.,
            Marvin,R.G., Kelly,R.A., Mondragón,A., Penner-Hahn,J.E. and
            O'Halloran,T.V.
  TITLE     Tetrathiomolybdate inhibits copper trafficking proteins through
            metal cluster formation
  JOURNAL   Science 327 (5963), 331-334 (2010)
   PUBMED   19965379
REFERENCE   2  (residues 1 to 73)
  AUTHORS   Xue,Y., Alvarez,H.M., Robinson,C.D., Mondragon,A. and
            O'Halloran,T.V.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2009)
COMMENT     Crystal structure of [TM][CuAtx1]3.
FEATURES             Location/Qualifiers
     source          1..73
                     /organism="Saccharomyces cerevisiae"
                     /db_xref="taxon:4932"
     SecStr          3..12
                     /sec_str_type="sheet"
                     /note="strand 13"
     Region          13..68
                     /region_name="HMA"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; cd00371"
                     /db_xref="CDD:238219"
     Site            order(13..15,18)
                     /site_type="metal-binding"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     Het             join(bond(15),bond(18))
                     /heterogen="(CU,6756)"
     Het             bond(15)
                     /heterogen="(CU,6757)"
     SecStr          17..27
                     /sec_str_type="helix"
                     /note="helix 7"
     SecStr          34..40
                     /sec_str_type="sheet"
                     /note="strand 14"
     SecStr          43..50
                     /sec_str_type="sheet"
                     /note="strand 15"
     SecStr          53..61
                     /sec_str_type="helix"
                     /note="helix 8"
     SecStr          66..73
                     /sec_str_type="sheet"
                     /note="strand 16"
ORIGIN      
        1 maeikhyqfn vvmtcsgcsg avnkvltkle pdvskidisl ekqlvdvytt lpydfileki
       61 kktgkevrsg kql
//
Feature
Display: FASTA GenBank Help
Details

Supplemental Content

Change region shown

Customize view

Protein 3D Structure

See all 6 structures...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
External link. Please review our privacy policy.