RecName: Full=Ubiquitin thioesterase OTUB2; AltName: Full=Deubiquitina - Protein

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OTUB2 silencing promotes ovarian cancer via mitochondrial metabolic reprogramming and can be synthetically targeted by CA9 inhibition. [Proc Natl Acad Sci U S A. 2024]
OTUB2 silencing promotes ovarian cancer via mitochondrial metabolic reprogramming and can be synthetically targeted by CA9 inhibition.
Nan Y, Wu X, Luo Q, Chang W, Zhao P, Zhang L, Liu Z. Proc Natl Acad Sci U S A. 2024 May 7; 121(19):e2315348121. Epub 2024 May 3.
Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. [Nat Commun. 2023]
Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Ikeuchi K, Ivic N, Buschauer R, Cheng J, Fröhlich T, Matsuo Y, Berninghausen O, Inada T, Becker T, Beckmann R. Nat Commun. 2023 May 12; 14(1):2730. Epub 2023 May 12.
Deubiquitinase OTUB2 promotes intrahepatic cholangiocarcinoma progression by stabilizing the CTNNB1-ZEB1 axis. [Exp Cell Res. 2023]
Deubiquitinase OTUB2 promotes intrahepatic cholangiocarcinoma progression by stabilizing the CTNNB1-ZEB1 axis.
Wang J, Dong Y, Wei Z, Zhang Y, Wu N, Zhang C, Zhang Y, Zi R, Hao J, Liang H, et al. Exp Cell Res. 2023 Apr 1; 425(1):113537. Epub 2023 Feb 27.

RefSeq protein
See the reference protein sequence for ubiquitin thioesterase OTUB2 (NP_075601.1).

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Q96DC9 [Domain Mapping of Disease Mut...]
Q96DC9
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
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RecName: Full=Ubiquitin thioesterase OTUB2; AltName: Full=Deubiquitinating enzym...
RecName: Full=Ubiquitin thioesterase OTUB2; AltName: Full=Deubiquitinating enzyme OTUB2; AltName: Full=OTU domain-containing ubiquitin aldehyde-binding protein 2; AltName: Full=Otubain-2; AltName: Full=Ubiquitin-specific-processing protease OTUB2
gi|44888285|sp|Q96DC9.2|OTUB2_HUMAN

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