RecName: Full=E3 ubiquitin-protein ligase SIAH2; AltName: Full=RING-ty - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

"The ubiquitin ligase SIAH2 is a female-specific regulator of circadian rhythms and metabolism". [PLoS Genet. 2022]
"The ubiquitin ligase SIAH2 is a female-specific regulator of circadian rhythms and metabolism".
Mekbib T, Suen TC, Rollins-Hairston A, Smith K, Armstrong A, Gray C, Owino S, Baba K, Baggs JE, Ehlen JC, et al. PLoS Genet. 2022 Jul; 18(7):e1010305. Epub 2022 Jul 5.
Siah2 modulates sex-dependent metabolic and inflammatory responses in adipose tissue to a high-fat diet challenge. [Biol Sex Differ. 2019]
Siah2 modulates sex-dependent metabolic and inflammatory responses in adipose tissue to a high-fat diet challenge.
Ghosh S, Taylor JL, Mendoza TM, Dang T, Burk DH, Yu Y, Kilroy G, Floyd ZE. Biol Sex Differ. 2019 Apr 15; 10(1):19. Epub 2019 Apr 15.
Siah2 Protein Mediates Early Events in Commitment to an Adipogenic Pathway. [J Biol Chem. 2016]
Siah2 Protein Mediates Early Events in Commitment to an Adipogenic Pathway.
Kilroy G, Burk DH, Floyd ZE. J Biol Chem. 2016 Dec 30; 291(53):27289-27297. Epub 2016 Nov 18.

RefSeq protein
See the reference protein sequence for E3 ubiquitin-protein ligase SIAH2 (NP_033200.2).

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Mouse Genome Informatics (MGI) [Mouse Genome Informatics (MGI)]
Mouse Genome Informatics (MGI)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=E3 ubiquitin-protein ligase SIAH2; AltName: Full=RING-type E3 ubiq...
RecName: Full=E3 ubiquitin-protein ligase SIAH2; AltName: Full=RING-type E3 ubiquitin transferase SIAH2; AltName: Full=Seven in absentia homolog 2; Short=Siah-2; Short=mSiah2
gi|46577337|sp|Q06986.2|SIAH2_MOUSE

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein