LOCUS WP_009956562 279 aa linear BCT 24-DEC-2024
DEFINITION MULTISPECIES: SDR family NAD(P)-dependent oxidoreductase
[Mycobacterium].
ACCESSION WP_009956562
VERSION WP_009956562.1
KEYWORDS RefSeq.
SOURCE Mycobacterium
ORGANISM Mycobacterium
Bacteria; Bacillati; Actinomycetota; Actinomycetes;
Mycobacteriales; Mycobacteriaceae.
REFERENCE 1 (residues 1 to 279)
AUTHORS Kallberg,Y., Oppermann,U. and Persson,B.
TITLE Classification of the short-chain dehydrogenase/reductase
superfamily using hidden Markov models
JOURNAL FEBS J 277 (10), 2375-2386 (2010)
PUBMED 20423462
REFERENCE 2 (residues 1 to 279)
AUTHORS Persson,B., Kallberg,Y., Bray,J.E., Bruford,E., Dellaporta,S.L.,
Favia,A.D., Duarte,R.G., Jornvall,H., Kavanagh,K.L., Kedishvili,N.,
Kisiela,M., Maser,E., Mindnich,R., Orchard,S., Penning,T.M.,
Thornton,J.M., Adamski,J. and Oppermann,U.
TITLE The SDR (short-chain dehydrogenase/reductase and related enzymes)
nomenclature initiative
JOURNAL Chem Biol Interact 178 (1-3), 94-98 (2009)
PUBMED 19027726
REFERENCE 3 (residues 1 to 279)
AUTHORS Kavanagh,K.L., Jornvall,H., Persson,B. and Oppermann,U.
TITLE Medium- and short-chain dehydrogenase/reductase gene and protein
families : the SDR superfamily: functional and structural diversity
within a family of metabolic and regulatory enzymes
JOURNAL Cell Mol Life Sci 65 (24), 3895-3906 (2008)
PUBMED 19011750
REFERENCE 4 (residues 1 to 279)
AUTHORS Ladenstein,R., Winberg,J.O. and Benach,J.
TITLE Medium- and short-chain dehydrogenase/reductase gene and protein
families : Structure-function relationships in short-chain alcohol
dehydrogenases
JOURNAL Cell Mol Life Sci 65 (24), 3918-3935 (2008)
PUBMED 19011748
REFERENCE 5 (residues 1 to 279)
AUTHORS Oppermann,U., Filling,C., Hult,M., Shafqat,N., Wu,X., Lindh,M.,
Shafqat,J., Nordling,E., Kallberg,Y., Persson,B. and Jornvall,H.
TITLE Short-chain dehydrogenases/reductases (SDR): the 2002 update
JOURNAL Chem Biol Interact 143-144, 247-253 (2003)
PUBMED 12604210
REFERENCE 6 (residues 1 to 279)
AUTHORS Jornvall,H., Persson,B., Krook,M., Atrian,S., Gonzalez-Duarte,R.,
Jeffery,J. and Ghosh,D.
TITLE Short-chain dehydrogenases/reductases (SDR)
JOURNAL Biochemistry 34 (18), 6003-6013 (1995)
PUBMED 7742302
COMMENT REFSEQ: This record represents a single, non-redundant, protein
sequence which may be annotated on many different RefSeq genomes
from the same, or different, species.
##Evidence-For-Name-Assignment-START##
Evidence Category :: Conserved Domain (CDD)
Evidence Accession :: Domain architecture ID 11416738
Evidence Source :: NCBI SPARCLE
##Evidence-For-Name-Assignment-END##
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..279
/organism="Mycobacterium"
/db_xref="taxon:1763"
Protein 1..279
/product="SDR family NAD(P)-dependent oxidoreductase"
/EC_number="1.1.1.-"
/GO_function="GO:0070403 - NAD+ binding [Evidence IEA];
GO:0070401 - NADP+ binding [Evidence IEA]; GO:0016491 -
oxidoreductase activity [Evidence IEA]"
/calculated_mol_wt=28913
Region 11..271
/region_name="YqjQ"
/note="Short-chain dehydrogenase [General function
prediction only]; COG0300"
/db_xref="CDD:440069"
ORIGIN
1 mfglnkpkis rgasavvtga gsgigaafav elgrrggavv csdidqtaaq ktadaiteqg
61 gkaiaircdv srfdevqala eqsqawfpaa ptlvinnagv gaggaaigda plddwawtlg
121 inlwgpihgc hvftpilrda esraprgiin vasaaafgaa pgmaaynvsk agvlslsetl
181 aaelagtpvr vtvlcptfvk tnilesgris eqsselatkl mrwtglsaek vartcldahd
241 rgelycmpqf dakvgwnikr lapqaytrta gllsrinlp
//