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NCBI Reference Sequence: NP_001015013.1
Identical Proteins FASTA Graphics
LOCUS NP_001015013 189 aa linear ROD 03-FEB-2024 DEFINITION leucine repeat adapter protein 25 [Rattus norvegicus]. ACCESSION NP_001015013 XP_219519 VERSION NP_001015013.1 DBSOURCE REFSEQ: accession NM_001015013.1 KEYWORDS RefSeq; RefSeq Select. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. REFERENCE 1 (residues 1 to 189) AUTHORS Lee,I.C.J., Leung,T. and Tan,I. TITLE Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics JOURNAL J Biol Chem 289 (39), 26989-27003 (2014) PUBMED 25107909 REMARK GeneRIF: the functional relevance of the LRAP25-MRCK complex in LIMK1-cofilin signaling and the importance of LRAP adaptors as key determinants of MRCK cellular localization and downstream specificities. REFERENCE 2 (residues 1 to 189) AUTHORS Kokura,K., Kim,H., Shinagawa,T., Khan,M.M., Nomura,T. and Ishii,S. TITLE The Ski-binding protein C184M negatively regulates tumor growth factor-beta signaling by sequestering the Smad proteins in the cytoplasm JOURNAL J Biol Chem 278 (22), 20133-20139 (2003) PUBMED 12646588 COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC093377.1. On Apr 20, 2005 this sequence version replaced XP_219519.2. ##Evidence-Data-START## Transcript exon combination :: BC093377.1, EV779280.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00132261, SAMD00132262 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## FEATURES Location/Qualifiers source 1..189 /organism="Rattus norvegicus" /db_xref="taxon:10116" /chromosome="1" /map="1q43" Protein 1..189 /product="leucine repeat adapter protein 25" /note="protein FAM89B; mammary tumor virus receptor 2" /calculated_mol_wt=20037 Site 28 /site_type="phosphorylation" /note="Phosphoserine. /evidence=ECO:0000250|UniProtKB:Q8N5H3; propagated from UniProtKB/Swiss-Prot (Q566R4.1)" Region 55..81 /region_name="Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite" /note="propagated from UniProtKB/Swiss-Prot (Q566R4.1)" Region 86..114 /region_name="LRR. /evidence=ECO:0000305|PubMed:25107909" /note="propagated from UniProtKB/Swiss-Prot (Q566R4.1)" Region 141..174 /region_name="Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite" /note="propagated from UniProtKB/Swiss-Prot (Q566R4.1)" Site 188 /site_type="phosphorylation" /note="Phosphoserine. /evidence=ECO:0000250|UniProtKB:Q8N5H3; propagated from UniProtKB/Swiss-Prot (Q566R4.1)" CDS 1..189 /gene="Fam89b" /gene_synonym="Mtvr2" /coded_by="NM_001015013.1:118..687" /db_xref="GeneID:309170" /db_xref="RGD:1311544" ORIGIN 1 mnglpsteap ggagcalagl pplprglsgl lnasggswre lervysqrsr ihdelsraar 61 apdgprhaag sanlgsaagp rrpvnldsal aalrkemvgl rqldmsllcq lwglyesiqd 121 ykhlcqdlsl cqdlssslhs dssyppdagl sdddeppdas lppdpppltv pqthnardqw 181 lqdafqisl //
Whole sequence Selected region from: to:
Conserved Domains
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