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pyridoxine biosynthesis protein SNZ2 [Saccharomyces cerevisiae S288C]

NCBI Reference Sequence: NP_014066.1

Identical Proteins FASTA Graphics 

LOCUS       NP_014066                298 aa            linear   PLN 17-DEC-2024
DEFINITION  pyridoxine biosynthesis protein SNZ2 [Saccharomyces cerevisiae
            S288C].
ACCESSION   NP_014066
VERSION     NP_014066.1
DBLINK      BioProject: PRJNA128
DBSOURCE    REFSEQ: accession NM_001183171.1
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (residues 1 to 298)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (residues 1 to 298)
  AUTHORS   Philippsen,P., Kleine,K., Pohlmann,R., Dusterhoft,A., Hamberg,K.,
            Hegemann,J.H., Obermaier,B., Urrestarazu,L.A., Aert,R.,
            Albermann,K., Altmann,R., Andre,B., Baladron,V., Ballesta,J.P.,
            Becam,A.M., Beinhauer,J., Boskovic,J., Buitrago,M.J., Bussereau,F.,
            Coster,F., Crouzet,M., D'Angelo,M., Dal Pero,F., De Antoni,A.,
            Hani,J. et al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV
            and its evolutionary implications
  JOURNAL   Nature 387 (6632 SUPPL), 93-98 (1997)
   PUBMED   9169873
REFERENCE   3  (residues 1 to 298)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   4  (residues 1 to 298)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 298)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (residues 1 to 298)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   7  (residues 1 to 298)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAY-2010) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   8  (residues 1 to 298)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. The reference
            sequence is identical to DAA10230.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Saccharomyces cerevisiae S288C"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="XIV"
     Protein         1..298
                     /product="pyridoxine biosynthesis protein SNZ2"
                     /EC_number="4.3.3.6"
                     /calculated_mol_wt=31902
     Region          6..298
                     /region_name="TIGR00343"
                     /note="pyridoxal 5'-phosphate synthase, synthase subunit
                     Pdx1"
                     /db_xref="CDD:129443"
     Site            order(21,40,78,150..152,213,232)
                     /site_type="active"
                     /db_xref="CDD:240078"
     Site            order(55,57,65,80,83..85,88,105..109,151..153,155,
                     158..159,162,215,218..219,260)
                     /site_type="other"
                     /note="multimer interface [polypeptide binding]"
                     /db_xref="CDD:240078"
     CDS             1..298
                     /gene="SNZ2"
                     /locus_tag="YNL333W"
                     /coded_by="NM_001183171.1:1..897"
                     /experiment="EXISTENCE:genetic interaction:GO:0008615
                     pyridoxine biosynthetic process [PMID:30498136]"
                     /experiment="EXISTENCE:genetic interaction:GO:0009228
                     thiamine biosynthetic process [PMID:30498136]"
                     /experiment="EXISTENCE:genetic interaction:GO:0042819
                     vitamin B6 biosynthetic process [PMID:12271461]"
                     /note="Protein involved in thiamine and pyridoxine
                     biosynthesis; member of a stationary phase-induced gene
                     family where transcriptional induction precedes the
                     diauxic shift; induced in the absence of thiamin in a
                     Thi2/3p-dependent manner and repressed in its presence;
                     forms a co-regulated gene pair with SNO2; interacts with
                     Thi11p; paralog of SNZ1 and SNZ3"
                     /db_xref="GeneID:855383"
                     /db_xref="SGD:S000005277"
ORIGIN      
        1 msefkvktgl aqmlkggvim dvvtpeqaii aeragacavm aleripadmr ksgqvcrmsd
       61 prmikeimea vsipvmakvr ighfveaqil eelqvdyide sevltpadwt hhiekhnfkv
      121 pfvcgakdlg ealrrinega amirtkgeag tgdvseavkh itkikaeiqq ykenlktesd
      181 faakatelrv pvdllkttls egklpvvnfa aggvatpada allmqlgceg vfvgsgifks
      241 sdpeklacai veatthydnp akllqissdl gdlmggisiq sineaggkng arlseigw
//
Feature
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Reference sequence information

  • RefSeq mRNA
    See reference mRNA sequence for the SNZ2 gene (NM_001183171.1).

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