LOCUS NP_014677 749 aa linear PLN 17-DEC-2024
DEFINITION putative palmitoyltransferase AKR2 [Saccharomyces cerevisiae
S288C].
ACCESSION NP_014677
VERSION NP_014677.1
DBLINK BioProject: PRJNA128
DBSOURCE REFSEQ: accession NM_001183453.1
KEYWORDS RefSeq.
SOURCE Saccharomyces cerevisiae S288C
ORGANISM Saccharomyces cerevisiae S288C
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (residues 1 to 749)
AUTHORS Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
Weng,S. and Cherry,J.M.
TITLE New data and collaborations at the Saccharomyces Genome Database:
updated reference genome, alleles, and the Alliance of Genome
Resources
JOURNAL Genetics 220 (4) (2022)
PUBMED 34897464
REFERENCE 2 (residues 1 to 749)
AUTHORS Dujon,B., Albermann,K., Aldea,M., Alexandraki,D., Ansorge,W.,
Arino,J., Benes,V., Bohn,C., Bolotin-Fukuhara,M., Bordonne,R.,
Boyer,J., Camasses,A., Casamayor,A., Casas,C., Cheret,G.,
Cziepluch,C., Daignan-Fornier,B., Dang,D.V., de Haan,M., Delius,H.,
Durand,P., Fairhead,C., Feldmann,H., Gaillon,L., Kleine,K. et al.
TITLE The nucleotide sequence of Saccharomyces cerevisiae chromosome XV
JOURNAL Nature 387 (6632 SUPPL), 98-102 (1997)
PUBMED 9169874
REFERENCE 3 (residues 1 to 749)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 4 (residues 1 to 749)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (17-DEC-2024) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 5 (residues 1 to 749)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (16-JAN-2015) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 6 (residues 1 to 749)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 7 (residues 1 to 749)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 8 (residues 1 to 749)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (27-MAY-2010) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 9 (residues 1 to 749)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (14-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
COMMENT REVIEWED REFSEQ: This record has been curated by SGD. The reference
sequence is identical to DAA10816.
##Genome-Annotation-Data-START##
Annotation Provider :: SGD
Annotation Status :: Full Annotation
Annotation Version :: R64-4-1
URL :: http://www.yeastgenome.org/
##Genome-Annotation-Data-END##
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..749
/organism="Saccharomyces cerevisiae S288C"
/strain="S288C"
/db_xref="taxon:559292"
/chromosome="XV"
Protein 1..749
/product="putative palmitoyltransferase AKR2"
/EC_number="2.3.1.225"
/calculated_mol_wt=85105
Region 6..292
/region_name="ANKYR"
/note="Ankyrin repeat [Signal transduction mechanisms];
COG0666"
/db_xref="CDD:440430"
Region 54..81
/region_name="ANK repeat"
/note="ANK repeat [structural motif]"
/db_xref="CDD:293786"
Site order(55..56,59..61,63..64,68,71,81,83,85,89..90,93..95,
97..98,102,105,115,117,119,123..124,127..129,131..132,136,
139,148)
/site_type="other"
/note="oligomer interface [polypeptide binding]"
/db_xref="CDD:293786"
Region 83..115
/region_name="ANK repeat"
/note="ANK repeat [structural motif]"
/db_xref="CDD:293786"
Region 117..148
/region_name="ANK repeat"
/note="ANK repeat [structural motif]"
/db_xref="CDD:293786"
Region 189..220
/region_name="ANK repeat"
/note="ANK repeat [structural motif]"
/db_xref="CDD:293786"
Region 222..247
/region_name="ANK repeat"
/note="ANK repeat [structural motif]"
/db_xref="CDD:293786"
Region 340..711
/region_name="COG5273"
/note="Uncharacterized protein containing DHHC-type Zn
finger [General function prediction only]"
/db_xref="CDD:227598"
CDS 1..749
/gene="AKR2"
/locus_tag="YOR034C"
/coded_by="NM_001183453.1:1..2250"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
vacuole membrane [PMID:19001347]"
/experiment="EXISTENCE:direct assay:GO:0005794 Golgi
apparatus [PMID:16647879]"
/note="Ankyrin repeat-containing protein; member of a
family of putative palmitoyltransferases containing an
Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; possibly
involved in constitutive endocytosis of Ste3p; AKR2 has a
paralog, AKR1, that arose from the whole genome
duplication"
/db_xref="GeneID:854199"
/db_xref="SGD:S000005560"
ORIGIN
1 mtsmsiidde nvkktsngaa vvtdvaqhav sdsdnnkaql lgdgsnteyv vdifieaakd
61 gdlkvvkdvv esgavdinnd ridelsglhw acinnrfsva kflllrganp nqaagpggat
121 alhwaarygn iyivdlllkh gadptlkdeq glnimhfsvy ssnillvvyv lyfvvnnndn
181 vdidskdnnn rtpllwaayq gdfltvelll kfgstvawtd nrgfnalhca lvggdqrvic
241 dlilsganfy ernnqkqdcf dlaegmgtks lfeqalqhhg ydrlgnqkdk lfkksshaqf
301 tiflspfllm vyiylislvl spvlaimlsl lvtvvmvntl kkfvlpclpr kntykvsltr
361 tpffsglfls tfcfliyiwt kklypysvsd ytmknvqflv tsfltvvlfl rlvrsdpgcl
421 ktddsltsiq etikqlidlg kfdrenfcve tlerkplrsk ysffsgalva rydhycpwiy
481 ndvglknhkl fvffavtvqy hmflfmwlcl ayfkktnyiy eqveeyarca llknetlckg
541 snydpstffl fiwisvnfiw lgamlivqff qilkgittpe lfilikeehk akfinlipfe
601 nsiytseskg vedsdmipeg psattithti sidgleprnr rrailsacfs mmginqwlvt
661 ikeivgithi lhgqvpqqhh ssllrsflvt nhwktnltdf wlnsdvtapl wqrffyssdt
721 skamlggtev dyyelyeypa regevlrpn
//