RecName: Full=Voltage-gated inwardly rectifying potassium channel KCNH - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

The scorpion toxin BeKm-1 blocks hERG cardiac potassium channels using an indispensable arginine residue. [FEBS Lett. 2024]
The scorpion toxin BeKm-1 blocks hERG cardiac potassium channels using an indispensable arginine residue.
Zavarzina II, Kuzmenkov AI, Dobrokhotov NA, Maleeva EE, Korolkova YV, Peigneur S, Tytgat J, Krylov NA, Vassilevski AA, Chugunov AO. FEBS Lett. 2024 Apr; 598(8):889-901. Epub 2024 Apr 2.
An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG. [BMC Biol. 2024]
An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG.
Liu Z, Wang F, Yuan H, Tian F, Yang C, Hu F, Liu Y, Tang M, Ping M, Kang C, et al. BMC Biol. 2024 Feb 5; 22(1):29. Epub 2024 Feb 5.
Clinical interpretation of KCNH2 variants using a robust PS3/BS3 functional patch-clamp assay. [HGG Adv. 2024]
Clinical interpretation of KCNH2 variants using a robust PS3/BS3 functional patch-clamp assay.
Thomson KL, Jiang C, Richardson E, Westphal DS, Burkard T, Wolf CM, Vatta M, Harrison SM, Ingles J, Bezzina CR, et al. HGG Adv. 2024 Apr 11; 5(2):100270. Epub 2024 Jan 14.

RefSeq protein isoforms
See 18 reference sequence protein isoforms for the KCNH2 gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Q12809 [Domain Mapping of Disease Mut...]
Q12809
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Voltage-gated inwardly rectifying potassium channel KCNH2; AltName...
RecName: Full=Voltage-gated inwardly rectifying potassium channel KCNH2; AltName: Full=Eag homolog; AltName: Full=Ether-a-go-go-related gene potassium channel 1; Short=ERG-1; Short=Eag-related protein 1; Short=Ether-a-go-go-related protein 1; Short=H-ERG; Short=hERG-1; Short=hERG1; AltName: Full=Potassium voltage-gated channel subfamily H member 2; AltName: Full=Voltage-gated potassium channel subunit Kv11.1
gi|7531135|sp|Q12809.1|KCNH2_HUMAN

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein