RecName: Full=Lymphokine-activated killer T-cell-originated protein ki - Protein

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TOPK promotes the development of psoriasis and worenine alleviates psoriasiform dermatitis by inhibiting TOPK activity. [J Eur Acad Dermatol Venereol. ...]
TOPK promotes the development of psoriasis and worenine alleviates psoriasiform dermatitis by inhibiting TOPK activity.
Lu H, Huang Y, Ni X, Ma T, Chang T, Liu M, Li N, Lu P, Yuan P, Liu L, et al. J Eur Acad Dermatol Venereol. 2024 May; 38(5):851-863. Epub 2023 Dec 22.
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway. [Cell Death Dis. 2023]
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway.
Wu W, Xu J, Gao D, Xie Z, Chen W, Li W, Yuan Q, Duan L, Zhang Y, Yang X, et al. Cell Death Dis. 2023 Jun 16; 14(6):364. Epub 2023 Jun 16.
TOPK inhibits TNF-α-induced granulosa cell apoptosis via regulation of SIRT1/p53. [Biochem Biophys Res Commun. 2023]
TOPK inhibits TNF-α-induced granulosa cell apoptosis via regulation of SIRT1/p53.
Joo NR, Park SA, Park JH, Oh SM. Biochem Biophys Res Commun. 2023 Jul 5; 664:128-135. Epub 2023 Apr 29.

RefSeq protein isoforms
See 3 reference sequence protein isoforms for the PBK gene.

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Q96KB5 [Domain Mapping of Disease Mut...]
Q96KB5
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Lymphokine-activated killer T-cell-originated protein kinase; AltN...
RecName: Full=Lymphokine-activated killer T-cell-originated protein kinase; AltName: Full=Cancer/testis antigen 84; Short=CT84; AltName: Full=MAPKK-like protein kinase; AltName: Full=Nori-3; AltName: Full=PDZ-binding kinase; AltName: Full=Spermatogenesis-related protein kinase; Short=SPK; AltName: Full=T-LAK cell-originated protein kinase
gi|83305809|sp|Q96KB5.3|TOPK_HUMAN

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