Transforming, acidic coiled-coil containing protein 3 [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

Cellular senescence gene TACC3 associated with colorectal cancer risk via genetic and DNA methylated alteration. [Arch Toxicol. 2024]
Cellular senescence gene TACC3 associated with colorectal cancer risk via genetic and DNA methylated alteration.
Shen H, Chen Y, Xu M, Zhou J, Huang C, Wang Z, Shao Y, Zhang H, Lu Y, Li S, et al. Arch Toxicol. 2024 May; 98(5):1499-1513. Epub 2024 Mar 14.
TACC3 is an independent prognostic marker, and knockdown of TACC3 enhances the efficacy of CDK1 inhibitor RO3306 in liver cancer cells. [J Biochem Mol Toxicol. 2023]
TACC3 is an independent prognostic marker, and knockdown of TACC3 enhances the efficacy of CDK1 inhibitor RO3306 in liver cancer cells.
Guo E, Yang J, Li L, Chen J, Liu H. J Biochem Mol Toxicol. 2023 Sep; 37(9):e23402. Epub 2023 Jun 21.
Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplification. [Cell Death Differ. 2023]
Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplification.
Saatci O, Akbulut O, Cetin M, Sikirzhytski V, Uner M, Lengerli D, O'Quinn EC, Romeo MJ, Caliskan B, Banoglu E, et al. Cell Death Differ. 2023 May; 30(5):1305-1319. Epub 2023 Mar 2.

RefSeq genomic sequence
See the genomic reference sequence for the TACC3 gene (NG_064424.1).
RefSeq protein isoforms
See 15 reference sequence protein isoforms for the TACC3 gene.

Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
Order cDNA Clone
Nucleotide NIH cDNA clone
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
Order cDNA clone
Order cDNA clone
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

Your browsing activity is empty.

Activity recording is turned off.

Protein