Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor - Protein

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PtdIns(3,4,5)P(3)-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis. [Proc Natl Acad Sci U S A. 2020]
PtdIns(3,4,5)P(3)-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis.
Srijakotre N, Liu HJ, Nobis M, Man J, Yip HYK, Papa A, Abud HE, Anderson KI, Welch HCE, Tiganis T, et al. Proc Natl Acad Sci U S A. 2020 Nov 10; 117(45):28056-28067. Epub 2020 Oct 23.
Identification of P-Rex1 as an anti-inflammatory and anti-fibrogenic target for pulmonary fibrosis. [Sci Rep. 2016]
Identification of P-Rex1 as an anti-inflammatory and anti-fibrogenic target for pulmonary fibrosis.
Liang Q, Cheng N, Zhang G, Liang Y, Qian F, Wu D, Ye RD. Sci Rep. 2016 May 13; 6:25785. Epub 2016 May 13.
A critical role for phosphatidylinositol (3,4,5)-trisphosphate-dependent Rac exchanger 1 in endothelial junction disruption and vascular hyperpermeability. [Circ Res. 2012]
A critical role for phosphatidylinositol (3,4,5)-trisphosphate-dependent Rac exchanger 1 in endothelial junction disruption and vascular hyperpermeability.
Naikawadi RP, Cheng N, Vogel SM, Qian F, Wu D, Malik AB, Ye RD. Circ Res. 2012 Dec 7; 111(12):1517-27. Epub 2012 Sep 10.

RefSeq protein
See the reference protein sequence for phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (NP_808450.2).

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Protein