LOCUS AIC51542 339 aa linear SYN 19-MAR-2015
DEFINITION DHRS7, partial [synthetic construct].
ACCESSION AIC51542
VERSION AIC51542.1
DBSOURCE accession KJ893957.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (residues 1 to 339)
AUTHORS Yang,X., Boehm,J.S., Yang,X., Salehi-Ashtiani,K., Hao,T., Shen,Y.,
Lubonja,R., Thomas,S.R., Alkan,O., Bhimdi,T., Green,T.M.,
Johannessen,C.M., Silver,S.J., Nguyen,C., Murray,R.R.,
Hieronymus,H., Balcha,D., Fan,C., Lin,C., Ghamsari,L., Vidal,M.,
Hahn,W.C., Hill,D.E. and Root,D.E.
TITLE A public genome-scale lentiviral expression library of human ORFs
JOURNAL Nat. Methods 8 (8), 659-661 (2011)
PUBMED 21706014
REMARK Publication Status: Online-Only
REFERENCE 2 (residues 1 to 339)
AUTHORS Root,D.
TITLE Direct Submission
JOURNAL Submitted (28-MAY-2014) Broad Institute, 75 Ames St., Cambridge, MA
02142, USA
COMMENT Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..339
/organism="Homo sapiens"
/db_xref="taxon:9606"
Protein 1..>339
/product="DHRS7"
Region 48..308
/region_name="11beta-HSD1_like_SDR_c"
/note="11beta-hydroxysteroid dehydrogenase type 1
(11beta-HSD1)-like, classical (c) SDRs; cd05332"
/db_xref="CDD:187593"
Site order(57..62,81..83,110..112,138..140,142,161,166,
188..190,203,207,234..237,239,241..242)
/site_type="other"
/note="NADP binding site [chemical binding]"
/db_xref="CDD:187593"
Site order(115,145..149,152,155..156,159..160,163..164,168,171,
194..201,204..205,208..209,211..213,215..217,219..220,
248..252,287,296..297,299,301..302,304..306,308)
/site_type="other"
/note="homodimer interface [polypeptide binding]"
/db_xref="CDD:187593"
Site order(140,143,190..192,197,200,203,234..236,241..242,
245..246)
/site_type="other"
/note="substrate binding site [chemical binding]"
/db_xref="CDD:187593"
Site order(162,190,203,207)
/site_type="active"
/db_xref="CDD:187593"
CDS 1..339
/coded_by="KJ893957.1:66..>1083"
/note="missing stop codon"
/transl_table=11
ORIGIN
1 mnwelllwll vlcalllllv qllrflradg dltllwaewq grrpeweltd mvvwvtgass
61 gigeelayql sklgvslvls arrvhelerv krrclengnl kekdilvlpl dltdtgshea
121 atkavlqefg ridilvnngg msqrslcmdt sldvyrklie lnylgtvslt kcvlphmier
181 kqgkivtvns ilgiisvpls igycaskhal rgffnglrte latypgiivs nicpgpvqsn
241 ivenslagev tktignngdq shkmttsrcv rlmlismand lkevwiseqp fllvtylwqy
301 mptwawwitn kmgkkrienf ksgvdadssy fkifktkhd
//