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DHRS7, partial [synthetic construct]

GenBank: AIC51542.1

Identical Proteins FASTA Graphics 

LOCUS       AIC51542                 339 aa            linear   SYN 19-MAR-2015
DEFINITION  DHRS7, partial [synthetic construct].
ACCESSION   AIC51542
VERSION     AIC51542.1
DBSOURCE    accession KJ893957.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 339)
  AUTHORS   Yang,X., Boehm,J.S., Yang,X., Salehi-Ashtiani,K., Hao,T., Shen,Y.,
            Lubonja,R., Thomas,S.R., Alkan,O., Bhimdi,T., Green,T.M.,
            Johannessen,C.M., Silver,S.J., Nguyen,C., Murray,R.R.,
            Hieronymus,H., Balcha,D., Fan,C., Lin,C., Ghamsari,L., Vidal,M.,
            Hahn,W.C., Hill,D.E. and Root,D.E.
  TITLE     A public genome-scale lentiviral expression library of human ORFs
  JOURNAL   Nat. Methods 8 (8), 659-661 (2011)
   PUBMED   21706014
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 339)
  AUTHORS   Root,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAY-2014) Broad Institute, 75 Ames St., Cambridge, MA
            02142, USA
COMMENT     Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
     Protein         1..>339
                     /product="DHRS7"
     Region          48..308
                     /region_name="11beta-HSD1_like_SDR_c"
                     /note="11beta-hydroxysteroid dehydrogenase type 1
                     (11beta-HSD1)-like, classical (c) SDRs; cd05332"
                     /db_xref="CDD:187593"
     Site            order(57..62,81..83,110..112,138..140,142,161,166,
                     188..190,203,207,234..237,239,241..242)
                     /site_type="other"
                     /note="NADP binding site [chemical binding]"
                     /db_xref="CDD:187593"
     Site            order(115,145..149,152,155..156,159..160,163..164,168,171,
                     194..201,204..205,208..209,211..213,215..217,219..220,
                     248..252,287,296..297,299,301..302,304..306,308)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:187593"
     Site            order(140,143,190..192,197,200,203,234..236,241..242,
                     245..246)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:187593"
     Site            order(162,190,203,207)
                     /site_type="active"
                     /db_xref="CDD:187593"
     CDS             1..339
                     /coded_by="KJ893957.1:66..>1083"
                     /note="missing stop codon"
                     /transl_table=11
ORIGIN      
        1 mnwelllwll vlcalllllv qllrflradg dltllwaewq grrpeweltd mvvwvtgass
       61 gigeelayql sklgvslvls arrvhelerv krrclengnl kekdilvlpl dltdtgshea
      121 atkavlqefg ridilvnngg msqrslcmdt sldvyrklie lnylgtvslt kcvlphmier
      181 kqgkivtvns ilgiisvpls igycaskhal rgffnglrte latypgiivs nicpgpvqsn
      241 ivenslagev tktignngdq shkmttsrcv rlmlismand lkevwiseqp fllvtylwqy
      301 mptwawwitn kmgkkrienf ksgvdadssy fkifktkhd
//
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