Warning: The NCBI web site requires JavaScript to function. more...

Result Filters

MCPH1 [Homo sapiens]

GenBank: AOA60066.1

GenPept Identical Proteins FASTA

Supplemental Content

Analyze this sequence

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

Protein 3D Structure

STRUCTURE OF HUMAN MICROCEPHALIN (MCPH1) TANDEM BRCT DOMAINS IN COMPLEX WITH A GAMMA-H2AX PHOSPHOPEPTIDE

PDB: 3SZM

Source: Homo sapiens

Method: X-ray Diffraction

Resolution: 2.63 Å

See all 8 structures...

Articles about the MCPH1 gene

MCPH1: A Novel Case Report and a Review of the Literature. [Genes (Basel). 2022]
MCPH1: A Novel Case Report and a Review of the Literature.
Caraffi SG, Pollazzon M, Farooq M, Fatima A, Larsen LA, Zuntini R, Napoli M, Garavelli L. Genes (Basel). 2022 Apr 2; 13(4). Epub 2022 Apr 2.
MCPH1, beyond its role deciding the brain size. [Aging (Albany NY). 2021]
MCPH1, beyond its role deciding the brain size.
Kristofova M, Wang ZQ. Aging (Albany NY). 2021 Oct 27; 13(20):23437-23439. Epub 2021 Oct 27.
BRIT-1 expression and its relationship with PARP-1 and CAF-1/p60 in cutaneous melanoma. [J Eur Acad Dermatol Venereol. ...]
BRIT-1 expression and its relationship with PARP-1 and CAF-1/p60 in cutaneous melanoma.
Russo D, Travaglino A, Varricchio S, Merolla F, Ilardi G, Raffone A, Scalvenzi M, Costa C, Fabbrocini G, Staibano S, et al. J Eur Acad Dermatol Venereol. 2021 Apr; 35(4):e254-e257. Epub 2020 Nov 3.

Reference sequence information

RefSeq protein isoforms
See 26 reference sequence protein isoforms for the MCPH1 gene.

More about the MCPH1 gene

This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory...
Also Known As: BRIT1, MCT

Related information

Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
PubMed (Weighted)
Links to pubmed

LinkOut to external resources

reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...