A Tryptophan 'Gate' in the CRISPR-Cas3 Nuclease Controls ssDNA Entry into the Nuclease Site, That When Removed Results in Nuclease Hyperactivity.
He L, Matošević ZJ, Mitić D, Markulin D, Killelea T, Matković M, Bertoša B, Ivančić-Baće I, Bolt EL. Int J Mol Sci. 2021 Mar 11; 22(6). Epub 2021 Mar 11.