KIAA0170 [Homo sapiens]

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MDC1 maintains active elongation complexes of RNA polymerase II. [Cell Rep. 2023]
MDC1 maintains active elongation complexes of RNA polymerase II.
Pappas G, Munk SHN, Watanabe K, Thomas Q, Gál Z, Gram HH, Lee M, Gómez-Cabello D, Kanellis DC, Olivares-Chauvet P, et al. Cell Rep. 2023 Jan 31; 42(1):111979. Epub 2023 Jan 12.
Targeting MDC1 promotes apoptosis and sensitizes Imatinib resistance in CML cells by mainly disrupting non-homologous end-joining repair. [Med Oncol. 2022]
Targeting MDC1 promotes apoptosis and sensitizes Imatinib resistance in CML cells by mainly disrupting non-homologous end-joining repair.
Liang Y, Qin Y, Jiang G, Feng W, Yuan Y. Med Oncol. 2022 Sep 29; 39(12):226. Epub 2022 Sep 29.
Functional defects of cancer-associated MDC1 mutations in DNA damage repair. [DNA Repair (Amst). 2022]
Functional defects of cancer-associated MDC1 mutations in DNA damage repair.
Xie R, Yan Z, Jing J, Wang Y, Zhang J, Li Y, Liu X, Yu X, Wu C. DNA Repair (Amst). 2022 Jun; 114:103330. Epub 2022 Apr 21.

RefSeq protein isoforms
See 134 reference sequence protein isoforms for the MDC1 gene.

Nucleotide
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Protein