rCG47746, isoform CRA_a [Rattus norvegicus]

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Cardiac manifestations of human ACTA2 variants recapitulated in a zebrafish model. [J Hum Genet. 2024]
Cardiac manifestations of human ACTA2 variants recapitulated in a zebrafish model.
Sebastian WA, Inoue M, Shimizu N, Sato R, Oguri S, Itonaga T, Kishimoto S, Shiraishi H, Hanada T, Ihara K. J Hum Genet. 2024 Apr; 69(3-4):133-138. Epub 2024 Feb 5.
A highly penetrant ACTA2 mutation of thoracic aortic disease. [J Cardiothorac Surg. 2023]
A highly penetrant ACTA2 mutation of thoracic aortic disease.
Bobba CM, Azarrafiy R, Spratt JR, Hendrickson J, Martin TD, Arnaoutakis GJ, Jeng EI, Beaver TM. J Cardiothorac Surg. 2023 Dec 4; 18(1):352. Epub 2023 Dec 4.
Smooth Muscle-Alpha Actin R149C Pathogenic Variant Downregulates Integrin Recruitment at Cell-Matrix Adhesions and Decreases Cellular Contractility. [Int J Mol Sci. 2023]
Smooth Muscle-Alpha Actin R149C Pathogenic Variant Downregulates Integrin Recruitment at Cell-Matrix Adhesions and Decreases Cellular Contractility.
Ojha KR, Kim H, Padgham S, Hopkins L, Zamen RJ, Chattopadhyay A, Han G, Milewicz DM, Massett MP, Trache A. Int J Mol Sci. 2023 Jun 1; 24(11). Epub 2023 Jun 1.

RefSeq protein
See the reference protein sequence for actin, aortic smooth muscle (NP_112266.1).

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Protein