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zinc finger protein 174 isoform 1 [Mus musculus]

NCBI Reference Sequence: NP_001074686.1

Identical Proteins FASTA Graphics 

LOCUS       NP_001074686             407 aa            linear   ROD 02-MAY-2024
DEFINITION  zinc finger protein 174 isoform 1 [Mus musculus].
ACCESSION   NP_001074686 XP_358903
VERSION     NP_001074686.1
DBSOURCE    REFSEQ: accession NM_001081217.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 407)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 407)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129021.4.
            
            On Feb 6, 2007 this sequence version replaced XP_358903.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC151078.1, AK141897.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 2.26 cM"
     Protein         1..407
                     /product="zinc finger protein 174 isoform 1"
                     /calculated_mol_wt=46967
     Region          42..152
                     /region_name="SCAN"
                     /note="leucine rich region; smart00431"
                     /db_xref="CDD:128708"
     Region          328..348
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(333,335,337,339..340,343..344,347,361,363,367..368,
                     371..372,375,389,391,393,395..396,399..400,403)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          352..>407
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          356..376
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          384..404
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..407
                     /gene="Zfp174"
                     /gene_synonym="Gm1754"
                     /coded_by="NM_001081217.2:633..1856"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS37238.1"
                     /db_xref="GeneID:385674"
                     /db_xref="MGI:MGI:2686600"
ORIGIN      
        1 maarmeitls thtedsdkqe rhiimkleen rgppqqkayp dpelsrqgfr hfcyqevsgp
       61 qealsclqql crqwlqpelh tkeqilellv meqflvilpp eiqaqvwhry pkssreivtl
      121 vedlhrtskk pkqwvtvcmq gqkvllektg aqlveqelrd fqpqtpsrdi qedsleepsc
      181 egsheqlsph hwektvlqep vlrltetess rmrgdkenpk qeeargakac tvlhgrpkgg
      241 tlhspeprgv tasdarllqw qvrppqspks lahyqkhcre leyisnplrg hplrelkrsr
      301 ggrrrslsgl lqclghqaah pakkpysced cgknftwnse lkrhrrvhtg erpyicgecg
      361 ncfgrqstlk lhqrihtgek pyqcshcgkc frqssnlhqh hrlhhgn
//
Feature
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Reference sequence information

  • RefSeq mRNA
    See reference mRNA sequence for the Zfp174 gene (NM_001081217.2).
  • RefSeq protein isoforms
    See the other reference sequence protein isoform for the Zfp174 gene (NP_001404568.1).

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