LOCUS NP_001074686 407 aa linear ROD 02-MAY-2024
DEFINITION zinc finger protein 174 isoform 1 [Mus musculus].
ACCESSION NP_001074686 XP_358903
VERSION NP_001074686.1
DBSOURCE REFSEQ: accession NM_001081217.2
KEYWORDS RefSeq; RefSeq Select.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (residues 1 to 407)
AUTHORS Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
Jackson,S.P. and Balmus,G.
CONSRTM Sanger Mouse Genetics Project
TITLE Genetic determinants of micronucleus formation in vivo
JOURNAL Nature 627 (8002), 130-136 (2024)
PUBMED 38355793
REFERENCE 2 (residues 1 to 407)
AUTHORS Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
McMahon,A.P. and Southard-Smith,E.M.
TITLE A genome-wide screen to identify transcription factors expressed in
pelvic Ganglia of the lower urinary tract
JOURNAL Front Neurosci 6, 130 (2012)
PUBMED 22988430
REMARK Publication Status: Online-Only
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AC129021.4.
On Feb 6, 2007 this sequence version replaced XP_358903.3.
Sequence Note: The RefSeq transcript and protein were derived from
genomic sequence to make the sequence consistent with the reference
genome assembly. The genomic coordinates used for the transcript
record were based on alignments.
##Evidence-Data-START##
Transcript exon combination :: BC151078.1, AK141897.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMN00849374, SAMN00849378
[ECO:0000348]
##Evidence-Data-END##
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on expression, longest protein
##RefSeq-Attributes-END##
FEATURES Location/Qualifiers
source 1..407
/organism="Mus musculus"
/strain="C57BL/6"
/db_xref="taxon:10090"
/chromosome="16"
/map="16 2.26 cM"
Protein 1..407
/product="zinc finger protein 174 isoform 1"
/calculated_mol_wt=46967
Region 42..152
/region_name="SCAN"
/note="leucine rich region; smart00431"
/db_xref="CDD:128708"
Region 328..348
/region_name="C2H2 Zn finger"
/note="C2H2 Zn finger [structural motif]"
/db_xref="CDD:275368"
Site order(333,335,337,339..340,343..344,347,361,363,367..368,
371..372,375,389,391,393,395..396,399..400,403)
/site_type="other"
/note="putative nucleic acid binding site [nucleotide
binding]"
/db_xref="CDD:275368"
Region 352..>407
/region_name="COG5048"
/note="FOG: Zn-finger [General function prediction only]"
/db_xref="CDD:227381"
Region 356..376
/region_name="C2H2 Zn finger"
/note="C2H2 Zn finger [structural motif]"
/db_xref="CDD:275368"
Region 384..404
/region_name="C2H2 Zn finger"
/note="C2H2 Zn finger [structural motif]"
/db_xref="CDD:275368"
CDS 1..407
/gene="Zfp174"
/gene_synonym="Gm1754"
/coded_by="NM_001081217.2:633..1856"
/note="isoform 1 is encoded by transcript variant 1"
/db_xref="CCDS:CCDS37238.1"
/db_xref="GeneID:385674"
/db_xref="MGI:MGI:2686600"
ORIGIN
1 maarmeitls thtedsdkqe rhiimkleen rgppqqkayp dpelsrqgfr hfcyqevsgp
61 qealsclqql crqwlqpelh tkeqilellv meqflvilpp eiqaqvwhry pkssreivtl
121 vedlhrtskk pkqwvtvcmq gqkvllektg aqlveqelrd fqpqtpsrdi qedsleepsc
181 egsheqlsph hwektvlqep vlrltetess rmrgdkenpk qeeargakac tvlhgrpkgg
241 tlhspeprgv tasdarllqw qvrppqspks lahyqkhcre leyisnplrg hplrelkrsr
301 ggrrrslsgl lqclghqaah pakkpysced cgknftwnse lkrhrrvhtg erpyicgecg
361 ncfgrqstlk lhqrihtgek pyqcshcgkc frqssnlhqh hrlhhgn
//