CASP8-associated protein 2 [Homo sapiens]

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CRISPRi screening identifies CASP8AP2 as an essential viability factor in lung cancer controlling tumor cell death via the AP-1 pathway. [Cancer Lett. 2023]
CRISPRi screening identifies CASP8AP2 as an essential viability factor in lung cancer controlling tumor cell death via the AP-1 pathway.
Myacheva K, Walsh A, Riester M, Pelos G, Carl J, Diederichs S. Cancer Lett. 2023 Jan 1; 552:215958. Epub 2022 Oct 14.
The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing. [PLoS One. 2017]
The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing.
Aik WS, Lin MH, Tan D, Tripathy A, Marzluff WF, Dominski Z, Chou CY, Tong L. PLoS One. 2017; 12(10):e0186034. Epub 2017 Oct 11.
Hypermethylation of two CpG sites upstream of CASP8AP2 promoter influences gene expression and treatment outcome in childhood acute lymphoblastic leukemia. [Leuk Res. 2013]
Hypermethylation of two CpG sites upstream of CASP8AP2 promoter influences gene expression and treatment outcome in childhood acute lymphoblastic leukemia.
Li ZG, Jiao Y, Li WJ, Deng GR, Cui L, Gao C, Zhao XX, Wu MY, Jia HT. Leuk Res. 2013 Oct; 37(10):1287-93. Epub 2013 Aug 15.

RefSeq mRNA
See reference mRNA sequence for the CASP8AP2 gene (NM_001137668.2).
RefSeq protein isoforms
See 40 reference sequence protein isoforms for the CASP8AP2 gene.

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NP_001131140 [Domain Mapping of Disease Mut...]
NP_001131140
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

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Protein