homeobox protein Nkx-2.5 isoform 3 [Homo sapiens]

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View conserved domains detected in this protein sequence using CD-search.
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Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Knockout of the Cardiac Transcription Factor NKX2-5 Results in Stem Cell-Derived Cardiac Cells with Typical Purkinje Cell-like Signal Transduction and Extracellular Matrix Formation. [Int J Mol Sci. 2023]
Knockout of the Cardiac Transcription Factor NKX2-5 Results in Stem Cell-Derived Cardiac Cells with Typical Purkinje Cell-like Signal Transduction and Extracellular Matrix Formation.
Disse P, Aymanns I, Mücher L, Sandmann S, Varghese J, Ritter N, Strutz-Seebohm N, Seebohm G, Peischard S. Int J Mol Sci. 2023 Aug 29; 24(17). Epub 2023 Aug 29.
Disease-associated non-coding variants alter NKX2-5 DNA-binding affinity. [Biochim Biophys Acta Gene Regu...]
Disease-associated non-coding variants alter NKX2-5 DNA-binding affinity.
Peña-Martínez EG, Rivera-Madera A, Pomales-Matos DA, Sanabria-Alberto L, Rosario-Cañuelas BM, Rodríguez-Ríos JM, Carrasquillo-Dones EA, Rodríguez-Martínez JA. Biochim Biophys Acta Gene Regul Mech. 2023 Mar; 1866(1):194906. Epub 2023 Jan 21.
A Novel Splicing Mutation c.335-1 G > A in the Cardiac Transcription Factor NKX2-5 Leads to Familial Atrial Septal Defect Through miR-19 and PYK2. [Stem Cell Rev Rep. 2022]
A Novel Splicing Mutation c.335-1 G > A in the Cardiac Transcription Factor NKX2-5 Leads to Familial Atrial Septal Defect Through miR-19 and PYK2.
Jia L, Limeng D, Xiaoyin T, Junwen W, Xintong Z, Gang X, Yun B, Hong G. Stem Cell Rev Rep. 2022 Dec; 18(8):2646-2661. Epub 2022 Jul 2.

RefSeq genomic sequence
See the genomic reference sequence for the NKX2-5 gene (NG_013340.1).
RefSeq mRNA
See reference mRNA sequence for the NKX2-5 gene (NM_001166176.2).
RefSeq protein isoforms
See 5 reference sequence protein isoforms for the NKX2-5 gene.

Ensembl [Ensembl]
Ensembl
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

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Protein