histone deacetylase 8 isoform 2 [Homo sapiens]

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HDAC8 as an emerging target in drug discovery with special emphasis on medicinal chemistry. [Future Med Chem. 2023]
HDAC8 as an emerging target in drug discovery with special emphasis on medicinal chemistry.
Rajaraman S, Balakrishnan R, Deshmukh D, Ganorkar A, Biswas S, Pulya S, Ghosh B. Future Med Chem. 2023 May; 15(10):885-908. Epub 2023 May 25.
Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages. [ChemMedChem. 2023]
Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages.
Noce B, Di Bello E, Zwergel C, Fioravanti R, Valente S, Rotili D, Masotti A, Salik Zeya Ansari M, Trisciuoglio D, Chakrabarti A, et al. ChemMedChem. 2023 Feb 1; 18(3):e202200510. Epub 2022 Nov 8.
HDAC8 Activates AKT through Upregulating PLCB1 and Suppressing DESC1 Expression in MEK1/2 Inhibition-Resistant Cells. [Cells. 2021]
HDAC8 Activates AKT through Upregulating PLCB1 and Suppressing DESC1 Expression in MEK1/2 Inhibition-Resistant Cells.
Ha SD, Lewin N, Li SSC, Kim SO. Cells. 2021 May 4; 10(5). Epub 2021 May 4.

RefSeq mRNA
See reference mRNA sequence for the HDAC8 gene (NM_001166418.2).
RefSeq protein isoforms
See 27 reference sequence protein isoforms for the HDAC8 gene.

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NP_001159890 [Domain Mapping of Disease Mut...]
NP_001159890
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

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Protein