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NCBI Reference Sequence: NP_001276750.1
Identical Proteins FASTA Graphics
LOCUS NP_001276750 660 aa linear ROD 01-AUG-2024 DEFINITION leucine-rich repeat-containing protein 43 isoform 2 [Mus musculus]. ACCESSION NP_001276750 XP_006530460 VERSION NP_001276750.1 DBSOURCE REFSEQ: accession NM_001289821.1 KEYWORDS RefSeq. SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. REFERENCE 1 (residues 1 to 660) AUTHORS Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E., Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B. TITLE Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo JOURNAL Genes Dev 20 (19), 2713-2727 (2006) PUBMED 17015433 COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK133051.1, AK167729.1 and DV646947.1. On Jan 31, 2014 this sequence version replaced XP_006530460.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK167318.1, AK167729.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## FEATURES Location/Qualifiers source 1..660 /organism="Mus musculus" /strain="C57BL/6" /db_xref="taxon:10090" /chromosome="5" /map="5 63.01 cM" Protein 1..660 /product="leucine-rich repeat-containing protein 43 isoform 2" /note="leucine-rich repeat-containing protein 43" /calculated_mol_wt=74026 Region 1..24 /region_name="Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite" /note="propagated from UniProtKB/Swiss-Prot (Q3V0L5.1)" Region 148..169 /region_name="LRR 1" /note="propagated from UniProtKB/Swiss-Prot (Q3V0L5.1)" Region 154..291 /region_name="PPP1R42" /note="protein phosphatase 1 regulatory subunit 42; cl42388" /db_xref="CDD:455733" Region 170..191 /region_name="LRR 2" /note="propagated from UniProtKB/Swiss-Prot (Q3V0L5.1)" Region 171..194 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275378" Region 194..213 /region_name="LRR 3" /note="propagated from UniProtKB/Swiss-Prot (Q3V0L5.1)" Region 195..221 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275378" Region 221..242 /region_name="LRR 4" /note="propagated from UniProtKB/Swiss-Prot (Q3V0L5.1)" Region 222..247 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275378" Region 248..259 /region_name="leucine-rich repeat" /note="leucine-rich repeat [structural motif]" /db_xref="CDD:275378" Region 374..407 /region_name="Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite" /note="propagated from UniProtKB/Swiss-Prot (Q3V0L5.1)" Region 526..563 /region_name="Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite" /note="propagated from UniProtKB/Swiss-Prot (Q3V0L5.1)" Region 609..633 /region_name="Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite" /note="propagated from UniProtKB/Swiss-Prot (Q3V0L5.1)" CDS 1..660 /gene="Lrrc43" /gene_synonym="Gm1061" /coded_by="NM_001289821.1:6..1988" /note="isoform 2 is encoded by transcript variant 2" /db_xref="CCDS:CCDS71662.1" /db_xref="GeneID:381741" /db_xref="MGI:MGI:2685907" ORIGIN 1 metsesstsd yrqtegegeg vpgtlstavc ehlrklclre fpcgigswnk srflpqkcrv 61 wrelvpkeee tlvpeeetve allglvrsnh spwamlkdas aedrflrela iqnplmikdt 121 ffysyfrslr vvnkgvslvd kdllkflkle elvlsankie eidannlppt lkvlelygnl 181 iasmeclcsa ppprlqhlgl ghnkllgple slyvtshnwp qlvsldlgfn nltdlqnmil 241 glstlrhlrl lvlqgnplsl vpyyrgftid slahlcvldd itvspnekhq frglnihgdl 301 lareaqfvvt ignvrgvlds sildpepgpd gpfisysyyv tydfvededm ernvsglvea 361 thhdsvldei dkhfsgtdee dqqedpldgr hrhrgrqrfh pgsteemske lsefiakems 421 qmaegsvesg itevdwsets isihsaplpq sidsseelak lrpkidiqlc pspgtvlfnt 481 vhkpwsdvip ctyemkhtlk elirvkafll agttilswpv vptpvesplp akkgkdnnkk 541 kepakdkvhk kkkepprelr qdppvltvlg sglvylepll ageavvstvc nfgvvrtlet 601 drlthardsk kvkkslkkdr sktvpptmes gyqpeplsve vqiqlhqyrs veeaflslid //
Whole sequence Selected region from: to:
Conserved Domains
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