6-phosphogluconate dehydrogenase, decarboxylating isoform 2 [Homo sapi - Protein

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6-Phosphogluconate dehydrogenase promotes glycolysis and fatty acid synthesis by inhibiting the AMPK pathway in lung adenocarcinoma cells. [Cancer Lett. 2024]
6-Phosphogluconate dehydrogenase promotes glycolysis and fatty acid synthesis by inhibiting the AMPK pathway in lung adenocarcinoma cells.
Wu J, Chen Y, Zou H, Xu K, Hou J, Wang M, Tian S, Gao M, Ren Q, Sun C, et al. Cancer Lett. 2024 Oct 1; 601:217177. Epub 2024 Aug 22.
Critical Role of 6-Phosphogluconate Dehydrogenase in TAp73-Mediated Cancer Cell Proliferation. [Mol Cancer Res. 2023]
Critical Role of 6-Phosphogluconate Dehydrogenase in TAp73-Mediated Cancer Cell Proliferation.
Qiao R, Wei M, Chen H, Zhang X, Zhang J, Gao L, Ma H, Wang Y, Li L. Mol Cancer Res. 2023 Aug 1; 21(8):825-835.
6PGD Upregulation is Associated with Chemo- and Immuno-Resistance of Renal Cell Carcinoma via AMPK Signaling-Dependent NADPH-Mediated Metabolic Reprograming. [Am J Med Sci. 2020]
6PGD Upregulation is Associated with Chemo- and Immuno-Resistance of Renal Cell Carcinoma via AMPK Signaling-Dependent NADPH-Mediated Metabolic Reprograming.
Cao J, Sun X, Zhang X, Chen D. Am J Med Sci. 2020 Sep; 360(3):279-286. Epub 2020 Jun 20.

RefSeq mRNA
See reference mRNA sequence for the PGD gene (NM_001304451.2).
RefSeq protein isoforms
See 3 reference sequence protein isoforms for the PGD gene.

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