ribonucleoside-diphosphate reductase large subunit isoform 2 [Homo sap - Protein

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Prognostic value of RRM1 and its effect on chemoresistance in pancreatic cancer. [Cancer Chemother Pharmacol. 2024]
Prognostic value of RRM1 and its effect on chemoresistance in pancreatic cancer.
Lin X, Tan Y, Pan L, Tian Z, Lin L, Su M, Ou G, Chen Y. Cancer Chemother Pharmacol. 2024 Mar; 93(3):237-251. Epub 2023 Dec 1.
RRM1 is mediated by histone acetylation through gemcitabine resistance and contributes to invasiveness and ECM remodeling in pancreatic cancer. [Int J Oncol. 2023]
RRM1 is mediated by histone acetylation through gemcitabine resistance and contributes to invasiveness and ECM remodeling in pancreatic cancer.
Ono H, Murase Y, Yamashita H, Kato T, Asano D, Ishikawa Y, Watanabe S, Ueda H, Akahoshi K, Ogawa K, et al. Int J Oncol. 2023 Apr; 62(4). Epub 2023 Mar 3.
RRM1 variants cause a mitochondrial DNA maintenance disorder via impaired de novo nucleotide synthesis. [J Clin Invest. 2022]
RRM1 variants cause a mitochondrial DNA maintenance disorder via impaired de novo nucleotide synthesis.
Shintaku J, Pernice WM, Eyaid W, Gc JB, Brown ZP, Juanola-Falgarona M, Torres-Torronteras J, Sommerville EW, Hellebrekers DM, Blakely EL, et al. J Clin Invest. 2022 Jul 1; 132(13).

RefSeq genomic sequence
See the genomic reference sequence for the RRM1 gene (NG_027992.2).
RefSeq mRNA
See reference mRNA sequence for the RRM1 gene (NM_001318064.1).
RefSeq protein isoforms
See 4 reference sequence protein isoforms for the RRM1 gene.

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Protein