nonsense-mediated mRNA decay factor SMG7 isoform 12 [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

SNPs at SMG7 Associated with Time from Biochemical Recurrence to Prostate Cancer Death. [Cancer Epidemiol Biomarkers Pr...]
SNPs at SMG7 Associated with Time from Biochemical Recurrence to Prostate Cancer Death.
Song X, Ru M, Steinsnyder Z, Tkachuk K, Kopp RP, Sullivan J, Gümüş ZH, Offit K, Joseph V, Klein RJ. Cancer Epidemiol Biomarkers Prev. 2022 Jul 1; 31(7):1466-1472.
Frameshift Mutations of SMG7 Essential for Nonsense-Mediated mRNA Decay in Gastric and Colorectal Cancers. [Pathol Oncol Res. 2017]
Frameshift Mutations of SMG7 Essential for Nonsense-Mediated mRNA Decay in Gastric and Colorectal Cancers.
Jo YS, Song SY, Kim MS, Yoo NJ, Lee SH. Pathol Oncol Res. 2017 Jan; 23(1):221-222. Epub 2016 Oct 22.
SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity. [Nat Commun. 2021]
SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity.
Boehm V, Kueckelmann S, Gerbracht JV, Kallabis S, Britto-Borges T, Altmüller J, Krüger M, Dieterich C, Gehring NH. Nat Commun. 2021 Jun 25; 12(1):3965. Epub 2021 Jun 25.

RefSeq genomic sequence
See the genomic reference sequence for the SMG7 gene (NG_029808.1).
RefSeq mRNA
See reference mRNA sequence for the SMG7 gene (NM_001394135.1).
RefSeq protein isoforms
See 37 reference sequence protein isoforms for the SMG7 gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed

Your browsing activity is empty.

Activity recording is turned off.

Protein