PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 3 [Homo - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Biallelic PAN2 variants in individuals with a syndromic neurodevelopmental disorder and multiple congenital anomalies. [Eur J Hum Genet. 2022]
Biallelic PAN2 variants in individuals with a syndromic neurodevelopmental disorder and multiple congenital anomalies.
Reuter MS, Zech M, Hempel M, Altmüller J, Heung T, Pölsler L, Santer R, Thiele H, Trost B, Kubisch C, et al. Eur J Hum Genet. 2022 May; 30(5):611-618. Epub 2022 Mar 18.
USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization. [Nat Commun. 2018]
USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization.
Yang S, Liu L, Cao C, Song N, Wang Y, Ma S, Zhang Q, Yu N, Ding X, Yang F, et al. Nat Commun. 2018 Mar 29; 9(1):1285. Epub 2018 Mar 29.
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover. [Nat Struct Mol Biol. 2005]
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover.
Yamashita A, Chang TC, Yamashita Y, Zhu W, Zhong Z, Chen CY, Shyu AB. Nat Struct Mol Biol. 2005 Dec; 12(12):1054-63. Epub 2005 Nov 13.

RefSeq mRNA
See reference mRNA sequence for the PAN2 gene (NM_001394700.1).
RefSeq protein isoforms
See 13 reference sequence protein isoforms for the PAN2 gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
CCDS
Link to Consensus CDS
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
OMIM
OMIM records associated with protein sequence
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed

Your browsing activity is empty.

Activity recording is turned off.

Protein