RAC-beta serine/threonine-protein kinase isoform 1 [Homo sapiens]

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Finnish-specific AKT2 gene variant leads to impaired insulin signalling in myotubes. [J Mol Endocrinol. 2023]
Finnish-specific AKT2 gene variant leads to impaired insulin signalling in myotubes.
Mäkinen S, Datta N, Rangarajan S, Nguyen YH, Olkkonen VM, Latva-Rasku A, Nuutila P, Laakso M, Koistinen HA. J Mol Endocrinol. 2023 Feb 1; 70(2). Epub 2023 Jan 4.
AKT serine/threonine kinase 2-mediated phosphorylation of fascin threonine 403 regulates esophageal cancer progression. [Int J Biochem Cell Biol. 2022]
AKT serine/threonine kinase 2-mediated phosphorylation of fascin threonine 403 regulates esophageal cancer progression.
Zhang ZD, Wen B, Li DJ, Deng DX, Wu XD, Cheng YW, Liao LD, Long L, Dong G, Xu LY, et al. Int J Biochem Cell Biol. 2022 Apr; 145:106188. Epub 2022 Feb 24.
Efficacy and safety of sirolimus therapy in familial hypoinsulinemic hypoglycemia caused by AKT2 mutation inherited from the mosaic father. [Eur J Med Genet. 2021]
Efficacy and safety of sirolimus therapy in familial hypoinsulinemic hypoglycemia caused by AKT2 mutation inherited from the mosaic father.
Dushar M, Nowaczyk J, Pyrżak B, Akopyan H, Śmigiel R, Walczak A, Rydzanicz M, Płoski R, Szczałuba K. Eur J Med Genet. 2021 Dec; 64(12):104368. Epub 2021 Oct 18.

RefSeq genomic sequence
See the genomic reference sequence for the AKT2 gene (NG_012038.2).
RefSeq mRNA
See reference mRNA sequence for the AKT2 gene (NM_001626.6).
RefSeq protein isoforms
See 4 reference sequence protein isoforms for the AKT2 gene.

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SNP
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NP_001617 [Domain Mapping of Disease Mut...]
NP_001617
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
AKT serine/threonine kinase 2 protein [Guide to Pharmacology]
AKT serine/threonine kinase 2 protein
Guide to Pharmacology
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Find Quality Antibodies [GeneTex Inc]
Find Quality Antibodies
GeneTex Inc
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

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Protein