serine/arginine-rich splicing factor 2 [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

SRSF2 plays an unexpected role as reader of m(5)C on mRNA, linking epitranscriptomics to cancer. [Mol Cell. 2023]
SRSF2 plays an unexpected role as reader of m(5)C on mRNA, linking epitranscriptomics to cancer.
Ma HL, Bizet M, Soares Da Costa C, Murisier F, de Bony EJ, Wang MK, Yoshimi A, Lin KT, Riching KM, Wang X, et al. Mol Cell. 2023 Dec 7; 83(23):4239-4254.e10.
SRSF2 mutation cooperates with ASXL1 truncated alteration to accelerate leukemogenesis. [Leukemia. 2024]
SRSF2 mutation cooperates with ASXL1 truncated alteration to accelerate leukemogenesis.
Sui P, Ge G, Chen S, Bai J, Rubalcava IP, Yang H, Guo Y, Zhang P, Li Y, Medina EA, et al. Leukemia. 2024 Feb; 38(2):408-411. Epub 2023 Nov 28.
SRSF2 mutation reduces polycythemia and impairs hematopoietic progenitor functions in JAK2V617F-driven myeloproliferative neoplasm. [Blood Cancer J. 2023]
SRSF2 mutation reduces polycythemia and impairs hematopoietic progenitor functions in JAK2V617F-driven myeloproliferative neoplasm.
Yang Y, Abbas S, Sayem MA, Dutta A, Mohi G. Blood Cancer J. 2023 Nov 27; 13(1):171. Epub 2023 Nov 27.

RefSeq mRNA
See reference mRNA sequence for the SRSF2 gene (NM_003016.5).
RefSeq protein isoforms
See the other reference sequence protein isoform for the SRSF2 gene (NP_001182356.1).

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CCDS
Link to Consensus CDS
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (UniProtKB)
Protein gi (refseq) to protein gi (UniProtKB)
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
SNP
Related SNPs

NP_003007 [Domain Mapping of Disease Mut...]
NP_003007
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Find Quality Antibodies [GeneTex Inc]
Find Quality Antibodies
GeneTex Inc

Your browsing activity is empty.

Activity recording is turned off.

Protein