cGMP-dependent protein kinase 1 isoform 2 [Homo sapiens]

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Increased endogenous PKG I activity attenuates EGF-induced proliferation and migration of epithelial ovarian cancer via the MAPK/ERK pathway. [Cell Death Dis. 2023]
Increased endogenous PKG I activity attenuates EGF-induced proliferation and migration of epithelial ovarian cancer via the MAPK/ERK pathway.
Lan T, Li Y, Wang Y, Wang ZC, Mu CY, Tao AB, Gong JL, Zhou Y, Xu H, Li SB, et al. Cell Death Dis. 2023 Jan 19; 14(1):39. Epub 2023 Jan 19.
Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G. [J Mol Biol. 2021]
Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G.
VanSchouwen B, Boulton S, Melacini G. J Mol Biol. 2021 Oct 15; 433(21):167202. Epub 2021 Aug 13.
Nociceptor-localized cGMP-dependent protein kinase I is a critical generator for central sensitization and neuropathic pain. [Pain. 2021]
Nociceptor-localized cGMP-dependent protein kinase I is a critical generator for central sensitization and neuropathic pain.
Wang F, Ma SB, Tian ZC, Cui YT, Cong XY, Wu WB, Wang FD, Li ZZ, Han WJ, Wang TZ, et al. Pain. 2021 Jan; 162(1):135-151.

RefSeq genomic sequence
See the genomic reference sequence for the PRKG1 gene (NG_029982.1).
RefSeq mRNA
See reference mRNA sequence for the PRKG1 gene (NM_006258.4).
RefSeq protein isoforms
See 9 reference sequence protein isoforms for the PRKG1 gene.

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NP_006249 [Domain Mapping of Disease Mut...]
NP_006249
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
Protein kinase G (PKG) 1 protein [Guide to Pharmacology]
Protein kinase G (PKG) 1 protein
Guide to Pharmacology
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Find Quality Antibodies [GeneTex Inc]
Find Quality Antibodies
GeneTex Inc

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