LOCUS NP_010194 484 aa linear PLN 17-DEC-2024
DEFINITION Nur1p [Saccharomyces cerevisiae S288C].
ACCESSION NP_010194
VERSION NP_010194.1
DBLINK BioProject: PRJNA128
DBSOURCE REFSEQ: accession NM_001180148.1
KEYWORDS RefSeq.
SOURCE Saccharomyces cerevisiae S288C
ORGANISM Saccharomyces cerevisiae S288C
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (residues 1 to 484)
AUTHORS Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
Weng,S. and Cherry,J.M.
TITLE New data and collaborations at the Saccharomyces Genome Database:
updated reference genome, alleles, and the Alliance of Genome
Resources
JOURNAL Genetics 220 (4) (2022)
PUBMED 34897464
REFERENCE 2 (residues 1 to 484)
AUTHORS Jacq,C., Alt-Morbe,J., Andre,B., Arnold,W., Bahr,A., Ballesta,J.P.,
Bargues,M., Baron,L., Becker,A., Biteau,N., Blocker,H., Blugeon,C.,
Boskovic,J., Brandt,P., Bruckner,M., Buitrago,M.J., Coster,F.,
Delaveau,T., del Rey,F., Dujon,B., Eide,L.G.,
Garcia-Cantalejo,J.M., Goffeau,A., Gomez-Peris,A., Zaccaria,P. et
al.
TITLE The nucleotide sequence of Saccharomyces cerevisiae chromosome IV
JOURNAL Nature 387 (6632 SUPPL), 75-78 (1997)
PUBMED 9169867
REFERENCE 3 (residues 1 to 484)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 4 (residues 1 to 484)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (17-DEC-2024) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 5 (residues 1 to 484)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (16-JAN-2015) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 6 (residues 1 to 484)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (06-FEB-2013) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 7 (residues 1 to 484)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 8 (residues 1 to 484)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 9 (residues 1 to 484)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
COMMENT REVIEWED REFSEQ: This record has been curated by SGD. The reference
sequence is identical to DAA11769.
##Genome-Annotation-Data-START##
Annotation Provider :: SGD
Annotation Status :: Full Annotation
Annotation Version :: R64-4-1
URL :: http://www.yeastgenome.org/
##Genome-Annotation-Data-END##
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..484
/organism="Saccharomyces cerevisiae S288C"
/strain="S288C"
/db_xref="taxon:559292"
/chromosome="IV"
Protein 1..484
/product="Nur1p"
/calculated_mol_wt=56756
Region 228..313
/region_name="DUF2418"
/note="Protein of unknown function (DUF2418); pfam10332"
/db_xref="CDD:431217"
CDS 1..484
/gene="NUR1"
/locus_tag="YDL089W"
/coded_by="NM_001180148.1:1..1455"
/experiment="EXISTENCE:direct assay:GO:0034399 nuclear
periphery [PMID:26928762|PMID:14562095]"
/experiment="EXISTENCE:mutant phenotype:GO:0007096
regulation of exit from mitosis [PMID:25569132]"
/experiment="EXISTENCE:mutant phenotype:GO:0043007
maintenance of rDNA [PMID:18997772]"
/note="Chromosome linkage inner nuclear membrane protein;
CLIP, involved in perinuclear chromosome tethering and
rDNA repeat stability; involved in regulating mitotic
exit; dephosphorylated by Cdc14p in anaphase, which
promotes timely rDNA segregation and allows mitotic
progression; interacts with Csm1p and Lrs4p; null mutant
has elevated levels of unequal sister-chromatid exchange;
GFP-fusion protein localizes to the nuclear periphery;
Cdc28p substrate"
/db_xref="GeneID:851469"
/db_xref="SGD:S000002247"
ORIGIN
1 mgsndlinea yddsevvgee resksawmkr wyqlltspld lqlvinekle minwdayaks
61 lakplgnflt ilffiirllq dnlikpnyyk lnvksgafdl sksnklkefd ylweisssfq
121 nnnqfyafqs wyfvtlrfln nlfrftifil lslnlyvsck fmfgyfktyn lfhlkkefns
181 pnltkhnlkd lskeyyediy kqslwsmlkh ffrgsrddgp hvnqnedeif fqlrkwiptn
241 fminlfvsfs ptaivflsfs dvsftsaiai vfhqyildyi itkrfqrsvd ddlilssaal
301 qeyedkhima rinqcsnidt lssamgtrsk tpriftthsl cgeeirevyn yekrefealp
361 kmtesvpgsr etrikdyggi sqvsdhqshp igfhysprms pyyrdkvldn nlaqsssnen
421 lekggaylpn qdqnrpsksl splrktplsa rqkrfegsef nvlnkndins ilrspkkkkn
481 yhkr
//