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GET complex subunit GET1 [Saccharomyces cerevisiae S288C]

NCBI Reference Sequence: NP_011495.1

Identical Proteins FASTA Graphics 

LOCUS       NP_011495                235 aa            linear   PLN 17-DEC-2024
DEFINITION  GET complex subunit GET1 [Saccharomyces cerevisiae S288C].
ACCESSION   NP_011495
VERSION     NP_011495.1
DBLINK      BioProject: PRJNA128
DBSOURCE    REFSEQ: accession NM_001180885.1
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (residues 1 to 235)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (residues 1 to 235)
  AUTHORS   Tettelin,H., Agostoni Carbone,M.L., Albermann,K., Albers,M.,
            Arroyo,J., Backes,U., Barreiros,T., Bertani,I., Bjourson,A.J.,
            Bruckner,M., Bruschi,C.V., Carignani,G., Castagnoli,L., Cerdan,E.,
            Clemente,M.L., Coblenz,A., Coglievina,M., Coissac,E., Defoor,E.,
            Del Bino,S., Delius,H., Delneri,D., de Wergifosse,P., Dujon,B.,
            Kleine,K. et al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome VII
  JOURNAL   Nature 387 (6632 SUPPL), 81-84 (1997)
   PUBMED   9169869
REFERENCE   3  (residues 1 to 235)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   4  (residues 1 to 235)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 235)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2015) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (residues 1 to 235)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   7  (residues 1 to 235)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   8  (residues 1 to 235)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. The reference
            sequence is identical to DAA08078.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..235
                     /organism="Saccharomyces cerevisiae S288C"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="VII"
     Protein         1..235
                     /product="GET complex subunit GET1"
                     /calculated_mol_wt=26961
     Region          7..191
                     /region_name="CHD5"
                     /note="CHD5-like protein; pfam04420"
                     /db_xref="CDD:427938"
     CDS             1..235
                     /gene="GET1"
                     /locus_tag="YGL020C"
                     /gene_synonym="MDM39"
                     /coded_by="NM_001180885.1:1..708"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961]"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:14562095|PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005789 endoplasmic
                     reticulum membrane [PMID:36640319]"
                     /experiment="EXISTENCE:direct assay:GO:0006890 retrograde
                     vesicle-mediated transport, Golgi to endoplasmic reticulum
                     [PMID:16269340]"
                     /experiment="EXISTENCE:direct assay:GO:0008320 protein
                     transmembrane transporter activity [PMID:36640319]"
                     /experiment="EXISTENCE:direct assay:GO:0097051
                     establishment of protein localization to endoplasmic
                     reticulum membrane [PMID:36640319]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006890
                     retrograde vesicle-mediated transport, Golgi to
                     endoplasmic reticulum [PMID:16269340]"
                     /experiment="EXISTENCE:genetic interaction:GO:0043495
                     protein-membrane adaptor activity [PMID:18724936]"
                     /experiment="EXISTENCE:genetic interaction:GO:0071816
                     tail-anchored membrane protein insertion into ER membrane
                     [PMID:18724936]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000423
                     mitophagy [PMID:29673596]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006890
                     retrograde vesicle-mediated transport, Golgi to
                     endoplasmic reticulum [PMID:16269340]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0032977
                     membrane insertase activity [PMID:25043001]"
                     /experiment="EXISTENCE:physical interaction:GO:0043529 GET
                     complex [PMID:16269340]"
                     /note="Subunit of the GET complex; involved in insertion
                     of tail-anchored proteins into the ER membrane; required
                     for the retrieval of HDEL proteins from the Golgi to the
                     ER in an ERD2 dependent fashion and for normal
                     mitochondrial morphology and inheritance; Get1p and Get2p
                     form an aqueous channel for protein translocation and
                     insertion into the membrane"
                     /db_xref="GeneID:852864"
                     /db_xref="SGD:S000002988"
ORIGIN      
        1 mhwaaavaif fivvtkflqy tnkyhekwis kfapgnelsk kylakvkerh elkefnnsis
       61 aqdnyakwtk nnrkldsldk einnlkdeiq senkafqahl hklrllaltv pffvfkimyg
      121 ktpvyklsss tstlfptfvs gvwsqgwlyv llhplrtisq kwhimegkfg askfddmalq
      181 svslgiwvwa lmnvingvef ivkqlfltpk meapasvetq eekaldavdd aiild
//
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Protein 3D Structure

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Reference sequence information

  • RefSeq mRNA
    See reference mRNA sequence for the GET1 gene (NM_001180885.1).

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