LOCUS NP_011495 235 aa linear PLN 17-DEC-2024
DEFINITION GET complex subunit GET1 [Saccharomyces cerevisiae S288C].
ACCESSION NP_011495
VERSION NP_011495.1
DBLINK BioProject: PRJNA128
DBSOURCE REFSEQ: accession NM_001180885.1
KEYWORDS RefSeq.
SOURCE Saccharomyces cerevisiae S288C
ORGANISM Saccharomyces cerevisiae S288C
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (residues 1 to 235)
AUTHORS Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
Weng,S. and Cherry,J.M.
TITLE New data and collaborations at the Saccharomyces Genome Database:
updated reference genome, alleles, and the Alliance of Genome
Resources
JOURNAL Genetics 220 (4) (2022)
PUBMED 34897464
REFERENCE 2 (residues 1 to 235)
AUTHORS Tettelin,H., Agostoni Carbone,M.L., Albermann,K., Albers,M.,
Arroyo,J., Backes,U., Barreiros,T., Bertani,I., Bjourson,A.J.,
Bruckner,M., Bruschi,C.V., Carignani,G., Castagnoli,L., Cerdan,E.,
Clemente,M.L., Coblenz,A., Coglievina,M., Coissac,E., Defoor,E.,
Del Bino,S., Delius,H., Delneri,D., de Wergifosse,P., Dujon,B.,
Kleine,K. et al.
TITLE The nucleotide sequence of Saccharomyces cerevisiae chromosome VII
JOURNAL Nature 387 (6632 SUPPL), 81-84 (1997)
PUBMED 9169869
REFERENCE 3 (residues 1 to 235)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 4 (residues 1 to 235)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (17-DEC-2024) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 5 (residues 1 to 235)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (16-JAN-2015) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 6 (residues 1 to 235)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 7 (residues 1 to 235)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 8 (residues 1 to 235)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
COMMENT REVIEWED REFSEQ: This record has been curated by SGD. The reference
sequence is identical to DAA08078.
##Genome-Annotation-Data-START##
Annotation Provider :: SGD
Annotation Status :: Full Annotation
Annotation Version :: R64-4-1
URL :: http://www.yeastgenome.org/
##Genome-Annotation-Data-END##
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..235
/organism="Saccharomyces cerevisiae S288C"
/strain="S288C"
/db_xref="taxon:559292"
/chromosome="VII"
Protein 1..235
/product="GET complex subunit GET1"
/calculated_mol_wt=26961
Region 7..191
/region_name="CHD5"
/note="CHD5-like protein; pfam04420"
/db_xref="CDD:427938"
CDS 1..235
/gene="GET1"
/locus_tag="YGL020C"
/gene_synonym="MDM39"
/coded_by="NM_001180885.1:1..708"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:14562095|PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005789 endoplasmic
reticulum membrane [PMID:36640319]"
/experiment="EXISTENCE:direct assay:GO:0006890 retrograde
vesicle-mediated transport, Golgi to endoplasmic reticulum
[PMID:16269340]"
/experiment="EXISTENCE:direct assay:GO:0008320 protein
transmembrane transporter activity [PMID:36640319]"
/experiment="EXISTENCE:direct assay:GO:0097051
establishment of protein localization to endoplasmic
reticulum membrane [PMID:36640319]"
/experiment="EXISTENCE:genetic interaction:GO:0006890
retrograde vesicle-mediated transport, Golgi to
endoplasmic reticulum [PMID:16269340]"
/experiment="EXISTENCE:genetic interaction:GO:0043495
protein-membrane adaptor activity [PMID:18724936]"
/experiment="EXISTENCE:genetic interaction:GO:0071816
tail-anchored membrane protein insertion into ER membrane
[PMID:18724936]"
/experiment="EXISTENCE:mutant phenotype:GO:0000423
mitophagy [PMID:29673596]"
/experiment="EXISTENCE:mutant phenotype:GO:0006890
retrograde vesicle-mediated transport, Golgi to
endoplasmic reticulum [PMID:16269340]"
/experiment="EXISTENCE:mutant phenotype:GO:0032977
membrane insertase activity [PMID:25043001]"
/experiment="EXISTENCE:physical interaction:GO:0043529 GET
complex [PMID:16269340]"
/note="Subunit of the GET complex; involved in insertion
of tail-anchored proteins into the ER membrane; required
for the retrieval of HDEL proteins from the Golgi to the
ER in an ERD2 dependent fashion and for normal
mitochondrial morphology and inheritance; Get1p and Get2p
form an aqueous channel for protein translocation and
insertion into the membrane"
/db_xref="GeneID:852864"
/db_xref="SGD:S000002988"
ORIGIN
1 mhwaaavaif fivvtkflqy tnkyhekwis kfapgnelsk kylakvkerh elkefnnsis
61 aqdnyakwtk nnrkldsldk einnlkdeiq senkafqahl hklrllaltv pffvfkimyg
121 ktpvyklsss tstlfptfvs gvwsqgwlyv llhplrtisq kwhimegkfg askfddmalq
181 svslgiwvwa lmnvingvef ivkqlfltpk meapasvetq eekaldavdd aiild
//