LOCUS NP_012489 409 aa linear PLN 17-DEC-2024
DEFINITION putative lipoate--protein ligase [Saccharomyces cerevisiae S288C].
ACCESSION NP_012489
VERSION NP_012489.2
DBLINK BioProject: PRJNA128
DBSOURCE REFSEQ: accession NM_001181479.1
KEYWORDS RefSeq.
SOURCE Saccharomyces cerevisiae S288C
ORGANISM Saccharomyces cerevisiae S288C
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (residues 1 to 409)
AUTHORS Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
Weng,S. and Cherry,J.M.
TITLE New data and collaborations at the Saccharomyces Genome Database:
updated reference genome, alleles, and the Alliance of Genome
Resources
JOURNAL Genetics 220 (4) (2022)
PUBMED 34897464
REFERENCE 2 (residues 1 to 409)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 3 (residues 1 to 409)
AUTHORS Galibert,F., Alexandraki,D., Baur,A., Boles,E., Chalwatzis,N.,
Chuat,J.C., Coster,F., Cziepluch,C., De Haan,M., Domdey,H.,
Durand,P., Entian,K.D., Gatius,M., Goffeau,A., Grivell,L.A.,
Hennemann,A., Herbert,C.J., Heumann,K., Hilger,F., Hollenberg,C.P.,
Huang,M.E., Jacq,C., Jauniaux,J.C., Katsoulou,C.,
Karpfinger-Hartl,L. et al.
TITLE Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
X
JOURNAL EMBO J. 15 (9), 2031-2049 (1996)
PUBMED 8641269
REFERENCE 4 (residues 1 to 409)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (17-DEC-2024) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 5 (residues 1 to 409)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 6 (residues 1 to 409)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (12-APR-2011) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 7 (residues 1 to 409)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (14-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
COMMENT REVIEWED REFSEQ: This record has been curated by SGD. The reference
sequence is identical to DAA08754.
On Dec 12, 2005 this sequence version replaced NP_012489.1.
##Genome-Annotation-Data-START##
Annotation Provider :: SGD
Annotation Status :: Full Annotation
Annotation Version :: R64-4-1
URL :: http://www.yeastgenome.org/
##Genome-Annotation-Data-END##
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..409
/organism="Saccharomyces cerevisiae S288C"
/strain="S288C"
/db_xref="taxon:559292"
/chromosome="X"
Protein 1..409
/product="putative lipoate--protein ligase"
/EC_number="6.3.1.20"
/calculated_mol_wt=46872
Region 117..409
/region_name="BPL_LplA_LipB"
/note="biotin-lipoate ligase family; cl14057"
/db_xref="CDD:449326"
Site order(155,188,193..197,201,203,240,249..253,265..267,269)
/site_type="active"
/db_xref="CDD:319742"
CDS 1..409
/gene="AIM22"
/locus_tag="YJL046W"
/gene_synonym="LIP3; RRG3"
/coded_by="NM_001181479.1:1..1230"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:19570983]"
/experiment="EXISTENCE:mutant phenotype:GO:0009249 protein
lipoylation [PMID:19570983]"
/note="Lipoate-protein ligase; octanoyl-CoA: protein
transferase required along with Lip2 and Lip5 for
lipoylation of Lat1p and Kgd2p; similar to E. coli LplA;
null mutant displays reduced frequency of mitochondrial
genome loss"
/db_xref="GeneID:853401"
/db_xref="SGD:S000003582"
ORIGIN
1 msmmlsnwal spryvgqrnl ihcttlfhtl trwakdaddk yhdinsmyen mftpsndnvs
61 ilqdegksdy dttkassmee disafnkdly nfynigyakq imsasqleni vkakgrfviq
121 slstspyynl alenyvfknt prakrgpdnc rllfyindrc avigknqnlw qevdlaklks
181 knfellrrfs gggtvlhdlg nvnysyltsr ekfetkffnk miikwlnsln pelrldlner
241 gdiiqdgfki sgsaykiagg kayhhatmll nadleqfsgl lepslpnnme wessgvhsvk
301 skiknvgiit pnqfiavvse rfqktfkvdg eipiyycdef ksindeikda mntlqseqwk
361 yfsgpkfsvk ikdkgltikv ekgmiydcdr ndliglefkg flenidsyt
//