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FG-nucleoporin NSP1 [Saccharomyces cerevisiae S288C]

NCBI Reference Sequence: NP_012494.3

Identical Proteins FASTA Graphics 

LOCUS       NP_012494                823 aa            linear   PLN 17-DEC-2024
DEFINITION  FG-nucleoporin NSP1 [Saccharomyces cerevisiae S288C].
ACCESSION   NP_012494
VERSION     NP_012494.3
DBLINK      BioProject: PRJNA128
DBSOURCE    REFSEQ: accession NM_001181474.3
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (residues 1 to 823)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (residues 1 to 823)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   3  (residues 1 to 823)
  AUTHORS   Galibert,F., Alexandraki,D., Baur,A., Boles,E., Chalwatzis,N.,
            Chuat,J.C., Coster,F., Cziepluch,C., De Haan,M., Domdey,H.,
            Durand,P., Entian,K.D., Gatius,M., Goffeau,A., Grivell,L.A.,
            Hennemann,A., Herbert,C.J., Heumann,K., Hilger,F., Hollenberg,C.P.,
            Huang,M.E., Jacq,C., Jauniaux,J.C., Katsoulou,C.,
            Karpfinger-Hartl,L. et al.
  TITLE     Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
            X
  JOURNAL   EMBO J. 15 (9), 2031-2049 (1996)
   PUBMED   8641269
REFERENCE   4  (residues 1 to 823)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 823)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (residues 1 to 823)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (12-APR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   7  (residues 1 to 823)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. The reference
            sequence is identical to DAA08759.
            
            On Jul 30, 2012 this sequence version replaced NP_012494.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..823
                     /organism="Saccharomyces cerevisiae S288C"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="X"
     Protein         1..823
                     /product="FG-nucleoporin NSP1"
                     /calculated_mol_wt=86385
     Region          61..>214
                     /region_name="PHA03255"
                     /note="BDLF3; Provisional"
                     /db_xref="CDD:165513"
     Region          <289..>602
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          620..731
                     /region_name="Nsp1_C"
                     /note="Nsp1-like C-terminal region; pfam05064"
                     /db_xref="CDD:461540"
     CDS             1..823
                     /gene="NSP1"
                     /locus_tag="YJL041W"
                     /coded_by="NM_001181474.3:1..2472"
                     /experiment="EXISTENCE:direct assay:GO:0005543
                     phospholipid binding [PMID:17897934]"
                     /experiment="EXISTENCE:direct assay:GO:0005643 nuclear
                     pore [PMID:10684247|PMID:2112428]"
                     /experiment="EXISTENCE:direct assay:GO:0017056 structural
                     constituent of nuclear pore [PMID:19098896|PMID:19680227]"
                     /experiment="EXISTENCE:direct assay:GO:0034399 nuclear
                     periphery [PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0044613 nuclear
                     pore central transport channel
                     [PMID:18046406|PMID:9813081|PMID:24574455]"
                     /experiment="EXISTENCE:direct assay:GO:0044615 nuclear
                     pore nuclear basket [PMID:9813081]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006607
                     NLS-bearing protein import into nucleus [PMID:15039779]"
                     /experiment="EXISTENCE:genetic interaction:GO:0016973
                     poly(A)+ mRNA export from nucleus [PMID:10952996]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000055
                     ribosomal large subunit export from nucleus
                     [PMID:11071906|PMID:9971735|PMID:11739405]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000056
                     ribosomal small subunit export from nucleus
                     [PMID:11739405]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006405 RNA
                     export from nucleus [PMID:11352936]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006409 tRNA
                     export from nucleus [PMID:8524308]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006606 protein
                     import into nucleus [PMID:12730220|PMID:2112428]"
                     /experiment="EXISTENCE:physical interaction:GO:0017056
                     structural constituent of nuclear pore
                     [PMID:19098896|PMID:17418788|PMID:12169684]"
                     /note="FG-nucleoporin component of central core of the
                     nuclear pore complex; also part of the nuclear pore
                     complex (NPC) nuclear basket; contributes directly to
                     nucleocytoplasmic transport and maintenance of the NPC
                     permeability barrier; found in stable complex with Nup82p,
                     Gle2p and two other FG-nucleoporins (Nup159p and Nup116p);
                     also found in stable complex with Nic96p and two other
                     FG-nucleoproteins (Nup49p and Nup57p)"
                     /db_xref="GeneID:853409"
                     /db_xref="SGD:S000003577"
ORIGIN      
        1 mnfntpqqnk tpfsfgtann nsnttnqnss tgagafgtgq stfgfnnsap nntnnanssi
       61 tpafgsnntg ntafgnsnpt snvfgsnnst tntfgsnsag tslfgsssaq qtksngtagg
      121 ntfgssslfn nstnsnttkp afgglnfggg nnttpsstgn antsnnlfga tanankpafs
      181 fgattnddkk tepdkpafsf nssvgnktda qapttgfsfg sqlggnktvn eaakpslsfg
      241 sgsaganpag asqpepttne pakpalsfgt atsdnkttnt tpsfsfgaks denkagatsk
      301 pafsfgakpe ekkddnsskp afsfgaksne dkqdgtakpa fsfgakpaek nnnetskpaf
      361 sfgaksdekk dgdaskpafs fgakpdenka satskpafsf gakpeekkdd nsskpafsfg
      421 aksnedkqdg takpafsfga kpaeknnnet skpafsfgak sdekkdgdas kpafsfgaks
      481 dekkdsdssk pafsfgtksn ekkdsgsskp afsfgakpde kkndevskpa fsfgakanek
      541 kesdesksaf sfgskptgke egdgakaais fgakpeeqks sdtskpaftf gaqkdnekkt
      601 eesstgksta dvkssdslkl nskpvelkpv sldnktlddl vtkwtnqlte sashfeqytk
      661 kinswdqvlv kggeqisqly sdavmaehsq nkidqslqyi erqqdelenf ldnfetktea
      721 llsdvvstss gaaannndqk rqqayktaqt ldenlnslss nlsslivein nvsntfnktt
      781 nidinneden iqlikilnsh fdalrslddn stslekqins ikk
//
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