LOCUS NP_012494 823 aa linear PLN 17-DEC-2024
DEFINITION FG-nucleoporin NSP1 [Saccharomyces cerevisiae S288C].
ACCESSION NP_012494
VERSION NP_012494.3
DBLINK BioProject: PRJNA128
DBSOURCE REFSEQ: accession NM_001181474.3
KEYWORDS RefSeq.
SOURCE Saccharomyces cerevisiae S288C
ORGANISM Saccharomyces cerevisiae S288C
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (residues 1 to 823)
AUTHORS Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
Weng,S. and Cherry,J.M.
TITLE New data and collaborations at the Saccharomyces Genome Database:
updated reference genome, alleles, and the Alliance of Genome
Resources
JOURNAL Genetics 220 (4) (2022)
PUBMED 34897464
REFERENCE 2 (residues 1 to 823)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 3 (residues 1 to 823)
AUTHORS Galibert,F., Alexandraki,D., Baur,A., Boles,E., Chalwatzis,N.,
Chuat,J.C., Coster,F., Cziepluch,C., De Haan,M., Domdey,H.,
Durand,P., Entian,K.D., Gatius,M., Goffeau,A., Grivell,L.A.,
Hennemann,A., Herbert,C.J., Heumann,K., Hilger,F., Hollenberg,C.P.,
Huang,M.E., Jacq,C., Jauniaux,J.C., Katsoulou,C.,
Karpfinger-Hartl,L. et al.
TITLE Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
X
JOURNAL EMBO J. 15 (9), 2031-2049 (1996)
PUBMED 8641269
REFERENCE 4 (residues 1 to 823)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (17-DEC-2024) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 5 (residues 1 to 823)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 6 (residues 1 to 823)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (12-APR-2011) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 7 (residues 1 to 823)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (14-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
COMMENT REVIEWED REFSEQ: This record has been curated by SGD. The reference
sequence is identical to DAA08759.
On Jul 30, 2012 this sequence version replaced NP_012494.2.
##Genome-Annotation-Data-START##
Annotation Provider :: SGD
Annotation Status :: Full Annotation
Annotation Version :: R64-4-1
URL :: http://www.yeastgenome.org/
##Genome-Annotation-Data-END##
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..823
/organism="Saccharomyces cerevisiae S288C"
/strain="S288C"
/db_xref="taxon:559292"
/chromosome="X"
Protein 1..823
/product="FG-nucleoporin NSP1"
/calculated_mol_wt=86385
Region 61..>214
/region_name="PHA03255"
/note="BDLF3; Provisional"
/db_xref="CDD:165513"
Region <289..>602
/region_name="PTZ00121"
/note="MAEBL; Provisional"
/db_xref="CDD:173412"
Region 620..731
/region_name="Nsp1_C"
/note="Nsp1-like C-terminal region; pfam05064"
/db_xref="CDD:461540"
CDS 1..823
/gene="NSP1"
/locus_tag="YJL041W"
/coded_by="NM_001181474.3:1..2472"
/experiment="EXISTENCE:direct assay:GO:0005543
phospholipid binding [PMID:17897934]"
/experiment="EXISTENCE:direct assay:GO:0005643 nuclear
pore [PMID:10684247|PMID:2112428]"
/experiment="EXISTENCE:direct assay:GO:0017056 structural
constituent of nuclear pore [PMID:19098896|PMID:19680227]"
/experiment="EXISTENCE:direct assay:GO:0034399 nuclear
periphery [PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0044613 nuclear
pore central transport channel
[PMID:18046406|PMID:9813081|PMID:24574455]"
/experiment="EXISTENCE:direct assay:GO:0044615 nuclear
pore nuclear basket [PMID:9813081]"
/experiment="EXISTENCE:genetic interaction:GO:0006607
NLS-bearing protein import into nucleus [PMID:15039779]"
/experiment="EXISTENCE:genetic interaction:GO:0016973
poly(A)+ mRNA export from nucleus [PMID:10952996]"
/experiment="EXISTENCE:mutant phenotype:GO:0000055
ribosomal large subunit export from nucleus
[PMID:11071906|PMID:9971735|PMID:11739405]"
/experiment="EXISTENCE:mutant phenotype:GO:0000056
ribosomal small subunit export from nucleus
[PMID:11739405]"
/experiment="EXISTENCE:mutant phenotype:GO:0006405 RNA
export from nucleus [PMID:11352936]"
/experiment="EXISTENCE:mutant phenotype:GO:0006409 tRNA
export from nucleus [PMID:8524308]"
/experiment="EXISTENCE:mutant phenotype:GO:0006606 protein
import into nucleus [PMID:12730220|PMID:2112428]"
/experiment="EXISTENCE:physical interaction:GO:0017056
structural constituent of nuclear pore
[PMID:19098896|PMID:17418788|PMID:12169684]"
/note="FG-nucleoporin component of central core of the
nuclear pore complex; also part of the nuclear pore
complex (NPC) nuclear basket; contributes directly to
nucleocytoplasmic transport and maintenance of the NPC
permeability barrier; found in stable complex with Nup82p,
Gle2p and two other FG-nucleoporins (Nup159p and Nup116p);
also found in stable complex with Nic96p and two other
FG-nucleoproteins (Nup49p and Nup57p)"
/db_xref="GeneID:853409"
/db_xref="SGD:S000003577"
ORIGIN
1 mnfntpqqnk tpfsfgtann nsnttnqnss tgagafgtgq stfgfnnsap nntnnanssi
61 tpafgsnntg ntafgnsnpt snvfgsnnst tntfgsnsag tslfgsssaq qtksngtagg
121 ntfgssslfn nstnsnttkp afgglnfggg nnttpsstgn antsnnlfga tanankpafs
181 fgattnddkk tepdkpafsf nssvgnktda qapttgfsfg sqlggnktvn eaakpslsfg
241 sgsaganpag asqpepttne pakpalsfgt atsdnkttnt tpsfsfgaks denkagatsk
301 pafsfgakpe ekkddnsskp afsfgaksne dkqdgtakpa fsfgakpaek nnnetskpaf
361 sfgaksdekk dgdaskpafs fgakpdenka satskpafsf gakpeekkdd nsskpafsfg
421 aksnedkqdg takpafsfga kpaeknnnet skpafsfgak sdekkdgdas kpafsfgaks
481 dekkdsdssk pafsfgtksn ekkdsgsskp afsfgakpde kkndevskpa fsfgakanek
541 kesdesksaf sfgskptgke egdgakaais fgakpeeqks sdtskpaftf gaqkdnekkt
601 eesstgksta dvkssdslkl nskpvelkpv sldnktlddl vtkwtnqlte sashfeqytk
661 kinswdqvlv kggeqisqly sdavmaehsq nkidqslqyi erqqdelenf ldnfetktea
721 llsdvvstss gaaannndqk rqqayktaqt ldenlnslss nlsslivein nvsntfnktt
781 nidinneden iqlikilnsh fdalrslddn stslekqins ikk
//