LOCUS NP_014728 350 aa linear PLN 17-DEC-2024
DEFINITION dolichyl-diphosphooligosaccharide--protein glycotransferase OST3
[Saccharomyces cerevisiae S288C].
ACCESSION NP_014728
VERSION NP_014728.1
DBLINK BioProject: PRJNA128
DBSOURCE REFSEQ: accession NM_001183504.1
KEYWORDS RefSeq.
SOURCE Saccharomyces cerevisiae S288C
ORGANISM Saccharomyces cerevisiae S288C
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (residues 1 to 350)
AUTHORS Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
Weng,S. and Cherry,J.M.
TITLE New data and collaborations at the Saccharomyces Genome Database:
updated reference genome, alleles, and the Alliance of Genome
Resources
JOURNAL Genetics 220 (4) (2022)
PUBMED 34897464
REFERENCE 2 (residues 1 to 350)
AUTHORS Dujon,B., Albermann,K., Aldea,M., Alexandraki,D., Ansorge,W.,
Arino,J., Benes,V., Bohn,C., Bolotin-Fukuhara,M., Bordonne,R.,
Boyer,J., Camasses,A., Casamayor,A., Casas,C., Cheret,G.,
Cziepluch,C., Daignan-Fornier,B., Dang,D.V., de Haan,M., Delius,H.,
Durand,P., Fairhead,C., Feldmann,H., Gaillon,L., Kleine,K. et al.
TITLE The nucleotide sequence of Saccharomyces cerevisiae chromosome XV
JOURNAL Nature 387 (6632 SUPPL), 98-102 (1997)
PUBMED 9169874
REFERENCE 3 (residues 1 to 350)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 4 (residues 1 to 350)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (17-DEC-2024) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 5 (residues 1 to 350)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (16-JAN-2015) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 6 (residues 1 to 350)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 7 (residues 1 to 350)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 8 (residues 1 to 350)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (27-MAY-2010) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 9 (residues 1 to 350)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (14-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
COMMENT REVIEWED REFSEQ: This record has been curated by SGD. The reference
sequence is identical to DAA10863.
##Genome-Annotation-Data-START##
Annotation Provider :: SGD
Annotation Status :: Full Annotation
Annotation Version :: R64-4-1
URL :: http://www.yeastgenome.org/
##Genome-Annotation-Data-END##
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..350
/organism="Saccharomyces cerevisiae S288C"
/strain="S288C"
/db_xref="taxon:559292"
/chromosome="XV"
Protein 1..350
/product="dolichyl-diphosphooligosaccharide--protein
glycotransferase OST3"
/calculated_mol_wt=39352
Region 26..340
/region_name="OST3_OST6"
/note="OST3 / OST6 family, transporter family; pfam04756"
/db_xref="CDD:461420"
CDS 1..350
/gene="OST3"
/locus_tag="YOR085W"
/coded_by="NM_001183504.1:1..1053"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0008250
oligosaccharyltransferase complex [PMID:10358084]"
/experiment="EXISTENCE:direct assay:GO:0015035
protein-disulfide reductase activity [PMID:23416356]"
/experiment="EXISTENCE:genetic interaction:GO:0006487
protein N-linked glycosylation [PMID:10358084]"
/experiment="EXISTENCE:genetic interaction:GO:0035269
protein O-linked mannosylation [PMID:22492205]"
/experiment="EXISTENCE:mutant phenotype:GO:0004579
dolichyl-diphosphooligosaccharide-protein glycotransferase
activity [PMID:7622558]"
/experiment="EXISTENCE:mutant phenotype:GO:0006486 protein
glycosylation [PMID:7622558]"
/experiment="EXISTENCE:mutant phenotype:GO:0006487 protein
N-linked glycosylation [PMID:28598353]"
/experiment="EXISTENCE:mutant phenotype:GO:0016020
membrane [PMID:7622558]"
/experiment="EXISTENCE:physical interaction:GO:0006487
protein N-linked glycosylation [PMID:9405463]"
/experiment="EXISTENCE:physical interaction:GO:0008250
oligosaccharyltransferase complex [PMID:9405463]"
/note="Gamma subunit of the oligosaccharyltransferase
complex of the ER lumen; complex catalyzes
asparagine-linked glycosylation of newly synthesized
proteins; Ost3p is important for N-glycosylation of a
subset of proteins including modification of Pmt2p at N131
and N403"
/db_xref="GeneID:854252"
/db_xref="SGD:S000005611"
ORIGIN
1 mnwlflvslv ffcgvsthpa lamssnrllk lankspkkii plkdssfeni lapphenayi
61 valftatape igcslclele seydtivasw fddhpdakss nsdtsifftk vnledpskti
121 pkafqffqln nvprlfifkp nspsildhsv isistdtgse rmkqiiqaik qfsqvndfsl
181 hlpmdwtpii tstiitfitv llfkkqsklm fsiissriiw atlstffiic misaymfnqi
241 rntqlagvgp kgevmyflpn efqhqfaiet qvmvliygtl aalvvvlvkg iqflrshlyp
301 etkkayfida ilasfcalfi yvffaalttv ftikspaypf pllrlsapfk
//