serine/threonine-protein kinase WNK3 isoform 1 [Homo sapiens]

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WNK3 inhibition elicits antitumor immunity by suppressing PD-L1 expression on tumor cells and activating T-cell function. [Exp Mol Med. 2022]
WNK3 inhibition elicits antitumor immunity by suppressing PD-L1 expression on tumor cells and activating T-cell function.
Yoon HJ, Kim GC, Oh S, Kim H, Kim YK, Lee Y, Kim MS, Kwon G, Ok YS, Kwon HK, et al. Exp Mol Med. 2022 Nov; 54(11):1913-1926. Epub 2022 Nov 10.
Rare pathogenic variants in WNK3 cause X-linked intellectual disability. [Genet Med. 2022]
Rare pathogenic variants in WNK3 cause X-linked intellectual disability.
Küry S, Zhang J, Besnard T, Caro-Llopis A, Zeng X, Robert SM, Josiah SS, Kiziltug E, Denommé-Pichon AS, Cogné B, et al. Genet Med. 2022 Sep; 24(9):1941-1951. Epub 2022 Jun 9.
Advances in the study of the role and molecular mechanism of with‑no‑lysine kinase 3 in nervous system diseases (Review). [Mol Med Rep. 2021]
Advances in the study of the role and molecular mechanism of with‑no‑lysine kinase 3 in nervous system diseases (Review).
Gong YT, Wu MY, Tang JF, Shen JC, Li J, Gao R, Dang BQ, Chen G. Mol Med Rep. 2021 May; 23(5). Epub 2021 Mar 24.

RefSeq mRNA
See reference mRNA sequence for the WNK3 gene (NM_020922.5).
RefSeq protein isoforms
See 41 reference sequence protein isoforms for the WNK3 gene.

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NP_065973 [Domain Mapping of Disease Mut...]
NP_065973
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
WNK lysine deficient protein kinase 3 protein [Guide to Pharmacology]
WNK lysine deficient protein kinase 3 protein
Guide to Pharmacology
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

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