Coupled folding-upon-binding of human tumor suppressor MIG6 to lung cancer EGFR kinase domain and molecular trimming/stapling of MIG6-derived β-hairpins to target the coupling event.
He Q, Xu S, Ma X, Ling T, Feng W, Lu X, Liu W, Chen Z. Eur Biophys J. 2023 Feb; 52(1-2):17-25. Epub 2022 Dec 22.