FERM domain-containing protein 8 [Mus musculus]

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The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth. [Life Sci Alliance. 2023]
The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth.
Badenes M, Burbridge E, Oikonomidi I, Amin A, de Carvalho É, Kosack L, Mariano C, Domingos P, Faísca P, Adrain C. Life Sci Alliance. 2023 Apr; 6(4). Epub 2023 Jan 31.
FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth. [Cell Rep. 2023]
FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth.
Yu M, Wu W, Sun Y, Yan H, Zhang L, Wang Z, Gong Y, Wang T, Li Q, Song J, et al. Cell Rep. 2023 Aug 29; 42(8):112886. Epub 2023 Jul 31.
Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway. [Blood. 2018]
Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.
Haxaire C, Hakobyan N, Pannellini T, Carballo C, McIlwain D, Mak TW, Rodeo S, Acharya S, Li D, Szymonifka J, et al. Blood. 2018 Sep 6; 132(10):1064-1074. Epub 2018 May 18.

RefSeq mRNA
See reference mRNA sequence for the Frmd8 gene (NM_026169.4).
RefSeq protein isoforms
See 3 reference sequence protein isoforms for the Frmd8 gene.

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BioSystems
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PubMed (Weighted)
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List of related structures

Ensembl [Ensembl]
Ensembl
Ensembl [Ensembl]
Ensembl
Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

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Protein