kelch-like protein 13 isoform a [Homo sapiens]

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A Cul3-based E3 ligase regulates mitosis and is required to maintain the spindle assembly checkpoint in human cells. [Cell Cycle. 2007]
A Cul3-based E3 ligase regulates mitosis and is required to maintain the spindle assembly checkpoint in human cells.
Sumara I, Peter M. Cell Cycle. 2007 Dec 15; 6(24):3004-10. Epub 2007 Sep 10.
Targeting Cul3-scaffold E3 ligase complex via KLHL substrate adaptors for cancer therapy. [Pharmacol Res. 2021]
Targeting Cul3-scaffold E3 ligase complex via KLHL substrate adaptors for cancer therapy.
Xiang S, Shi X, Chen P, Chen Y, Bing S, Jin X, Cao J, Wang J, Yang B, Shao X, et al. Pharmacol Res. 2021 Jul; 169:105616. Epub 2021 Apr 17.
Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation. [J Biol Chem. 2019]
Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation.
Frendo-Cumbo S, Jaldin-Fincati JR, Coyaud E, Laurent EMN, Townsend LK, Tan JMJ, Xavier RJ, Pillon NJ, Raught B, Wright DC, et al. J Biol Chem. 2019 Nov 1; 294(44):16172-16185. Epub 2019 Sep 12.

RefSeq genomic sequence
See the genomic reference sequence for the KLHL13 gene (NG_016759.2).
RefSeq mRNA
See reference mRNA sequence for the KLHL13 gene (NM_033495.4).
RefSeq protein isoforms
See 9 reference sequence protein isoforms for the KLHL13 gene.

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NP_277030 [Domain Mapping of Disease Mut...]
NP_277030
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

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Protein