The rebalanced pathway significantly enhances acetoin production by disruption of acetoin reductase gene and moderate-expression of a new water-forming NADH oxidase in Bacillus subtilis.
Zhang X, Zhang R, Bao T, Rao Z, Yang T, Xu M, Xu Z, Li H, Yang S. Metab Eng. 2014 May; 23:34-41. Epub 2014 Feb 10.