Studies of Schizosaccharomyces pombe TFIIE indicate conformational and functional changes in RNA polymerase II at transcription initiation.
Hayashi K, Watanabe T, Tanaka A, Furumoto T, Sato-Tsuchiya C, Kimura M, Yokoi M, Ishihama A, Hanaoka F, Ohkuma Y. Genes Cells. 2005 Mar; 10(3):207-24.