alpha-2-macroglobulin-like protein 1 isoform 1 precursor [Homo sapiens - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

A2ML1 Inhibits Esophageal Squamous Cell Carcinoma Progression and Serves as a Novel Prognostic Biomarker. [Can J Gastroenterol Hepatol. 2...]
A2ML1 Inhibits Esophageal Squamous Cell Carcinoma Progression and Serves as a Novel Prognostic Biomarker.
Zhang X, Tang C, Lian J, Jiang Y. Can J Gastroenterol Hepatol. 2023; 2023:5557546. Epub 2023 Nov 3.
Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family. [Nat Commun. 2022]
Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.
Nielsen NS, Zarantonello A, Harwood SL, Jensen KT, Kjøge K, Thøgersen IB, Schauser L, Karlsen JL, Andersen GR, Enghild JJ. Nat Commun. 2022 May 31; 13(1):3033. Epub 2022 May 31.
The clinical significance of A2ML1 variants in Noonan syndrome has to be reconsidered. [Eur J Hum Genet. 2021]
The clinical significance of A2ML1 variants in Noonan syndrome has to be reconsidered.
Brinkmann J, Lissewski C, Pinna V, Vial Y, Pantaleoni F, Lepri F, Daniele P, Burnyte B, Cuturilo G, Fauth C, et al. Eur J Hum Genet. 2021 Mar; 29(3):524-527. Epub 2020 Oct 20.

RefSeq genomic sequence
See the genomic reference sequence for the A2ML1 gene (NG_042857.2).
RefSeq mRNA
See reference mRNA sequence for the A2ML1 gene (NM_144670.6).
RefSeq protein isoforms
See 12 reference sequence protein isoforms for the A2ML1 gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
CCDS
Link to Consensus CDS
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
OMIM
OMIM records associated with protein sequence
Protein (UniProtKB)
Protein gi (refseq) to protein gi (UniProtKB)
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed

Your browsing activity is empty.

Activity recording is turned off.

Protein