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olfactory receptor 1143 [Mus musculus]

NCBI Reference Sequence: NP_666405.1

Identical Proteins FASTA Graphics 

LOCUS       NP_666405                314 aa            linear   ROD 26-OCT-2024
DEFINITION  olfactory receptor 1143 [Mus musculus].
ACCESSION   NP_666405
VERSION     NP_666405.1
DBSOURCE    REFSEQ: accession NM_146293.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 314)
  AUTHORS   Olender,T., Jones,T.E.M., Bruford,E. and Lancet,D.
  TITLE     A unified nomenclature for vertebrate olfactory receptors
  JOURNAL   BMC Evol Biol 20 (1), 42 (2020)
   PUBMED   32295537
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 314)
  AUTHORS   Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
            Walker,M., Williams,E.M. and Trask,B.J.
  TITLE     Odorant receptor expressed sequence tags demonstrate olfactory
            expression of over 400 genes, extensive alternate splicing and
            unequal expression levels
  JOURNAL   Genome Biol 4 (11), R71 (2003)
   PUBMED   14611657
REFERENCE   3  (residues 1 to 314)
  AUTHORS   Young,J.M., Friedman,C., Williams,E.M., Ross,J.A., Tonnes-Priddy,L.
            and Trask,B.J.
  TITLE     Different evolutionary processes shaped the mouse and human
            olfactory receptor gene families
  JOURNAL   Hum Mol Genet 11 (5), 535-546 (2002)
   PUBMED   11875048
  REMARK    Erratum:[Hum Mol Genet. 2002 Jul 1;11(14):1683.]
REFERENCE   4  (residues 1 to 314)
  AUTHORS   Zhang,X. and Firestein,S.
  TITLE     The olfactory receptor gene superfamily of the mouse
  JOURNAL   Nat Neurosci 5 (2), 124-133 (2002)
   PUBMED   11802173
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB173239.1 and AL929424.7.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Mus musculus"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 49.96 cM"
     Protein         1..314
                     /product="olfactory receptor 1143"
                     /note="olfactory receptor MOR177-14;
                     GA_x6K02T2Q125-49303473-49304405"
                     /calculated_mol_wt=35082
     Region          16..306
                     /region_name="7tmA_OR5C1-like"
                     /note="olfactory receptor subfamily 5C1 and related
                     proteins, member of the class A family of
                     seven-transmembrane G protein-coupled receptors; cd15945"
                     /db_xref="CDD:320611"
     Region          30..56
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:320611"
     Region          63..89
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:320611"
     Site            order(85,88..89,101..106,108..109,112,157,159..163,199,
                     202..204,206..208,210..211,256,259..260,262..263,266,
                     272..273,275..277,280,283..284)
                     /site_type="other"
                     /note="putative ligand binding pocket [chemical binding]"
                     /db_xref="CDD:320611"
     Region          101..131
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:320611"
     Region          144..165
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:320611"
     Region          199..229
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:320611"
     Region          236..266
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:320611"
     Region          273..298
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:320611"
     CDS             1..314
                     /gene="Or5w18"
                     /gene_synonym="MOR177-14; Olfr1143"
                     /coded_by="NM_146293.2:1..945"
                     /db_xref="CCDS:CCDS16309.1"
                     /db_xref="GeneID:258290"
                     /db_xref="MGI:MGI:3030977"
ORIGIN      
        1 mqrrmegenc ssftefilmg itnnsevkvv lftifllvyl inlignlgmi llikvdpqlq
       61 tpmyfflsnl sfcdlcysta vgpkmlmdif gndksiqffg calqffisct fvdsecilla
      121 vmafdryqai snpllyttnm snrlcsllva gvyfvgvads lihttltfhl cfcgsneidh
      181 ffcdippill lscsdtqvne laiftifgfi elstisgvlv sycyiissvl kissaggrfk
      241 afstcashlt avaifqgtvl fmyfrpsssy sldqdkmssl fyilvipmln pliyslrnkd
      301 vkealknlkn krcc
//
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Reference sequence information

  • RefSeq mRNA
    See reference mRNA sequence for the Or5w18 gene (NM_146293.2).

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