neprilysin 5, isoform D [Drosophila melanogaster]

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Articles about the Nep5 gene

Overexpression of neprilysin reduces alzheimer amyloid-beta42 (Abeta42)-induced neuron loss and intraneuronal Abeta42 deposits but causes a reduction in cAMP-responsive element-binding protein-mediated transcription, age-dependent axon pathology, and premature death in Drosophila. [J Biol Chem. 2008]
Overexpression of neprilysin reduces alzheimer amyloid-beta42 (Abeta42)-induced neuron loss and intraneuronal Abeta42 deposits but causes a reduction in cAMP-responsive element-binding protein-mediated transcription, age-dependent axon pathology, and premature death in Drosophila.
Iijima-Ando K, Hearn SA, Granger L, Shenton C, Gatt A, Chiang HC, Hakker I, Zhong Y, Iijima K. J Biol Chem. 2008 Jul 4; 283(27):19066-76. Epub 2008 May 7.
The Drosophila Neprilysin 4 gene is essential for sperm function following sperm transfer to females. [Genes Genet Syst. 2021]
The Drosophila Neprilysin 4 gene is essential for sperm function following sperm transfer to females.
Ohsako T, Shirakami M, Oiwa K, Ibaraki K, Karr TL, Tomaru M, Sanuki R, Takano-Shimizu-Kouno T. Genes Genet Syst. 2021 Dec 16; 96(4):177-186. Epub 2021 Sep 24.
Neprilysins: an evolutionarily conserved family of metalloproteases that play important roles in reproduction in Drosophila. [Genetics. 2014]
Neprilysins: an evolutionarily conserved family of metalloproteases that play important roles in reproduction in Drosophila.
Sitnik JL, Francis C, Hens K, Huybrechts R, Wolfner MF, Callaerts P. Genetics. 2014 Mar; 196(3):781-97. Epub 2014 Jan 6.

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Reference sequence information

RefSeq mRNA
See reference mRNA sequence for the Nep5 gene (NM_170307.2).
RefSeq protein isoforms
See 4 reference sequence protein isoforms for the Nep5 gene.

More about the Nep5 gene

Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in membrane. Pred...
Also Known As: Dmel_CG6265, CG6265, Dm...

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Articles about the Nep5 gene

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