LOCUS NP_775582 243 aa linear ROD 02-MAY-2024
DEFINITION juxtaposed with another zinc finger protein 1 isoform 1 [Mus
musculus].
ACCESSION NP_775582
VERSION NP_775582.2
DBSOURCE REFSEQ: accession NM_173406.4
KEYWORDS RefSeq; RefSeq Select.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (residues 1 to 243)
AUTHORS Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
Jackson,S.P. and Balmus,G.
CONSRTM Sanger Mouse Genetics Project
TITLE Genetic determinants of micronucleus formation in vivo
JOURNAL Nature 627 (8002), 130-136 (2024)
PUBMED 38355793
REFERENCE 2 (residues 1 to 243)
AUTHORS Lee,H.Y., Jang,H.R., Li,H., Samuel,V.T., Dudek,K.D.,
Osipovich,A.B., Magnuson,M.A., Sklar,J. and Shulman,G.I.
TITLE Deletion of Jazf1 gene causes early growth retardation and insulin
resistance in mice
JOURNAL Proc Natl Acad Sci U S A 119 (49), e2213628119 (2022)
PUBMED 36442127
REMARK GeneRIF: Deletion of Jazf1 gene causes early growth retardation and
insulin resistance in mice.
REFERENCE 3 (residues 1 to 243)
AUTHORS Wang,Q., Dong,Y. and Wang,H.
TITLE microRNA-19b-3p-containing extracellular vesicles derived from
macrophages promote the development of atherosclerosis by targeting
JAZF1
JOURNAL J Cell Mol Med 26 (1), 48-59 (2022)
PUBMED 34910364
REMARK GeneRIF: microRNA-19b-3p-containing extracellular vesicles derived
from macrophages promote the development of atherosclerosis by
targeting JAZF1.
REFERENCE 4 (residues 1 to 243)
AUTHORS Jeong,J., Jang,S., Park,S., Kwon,W., Kim,S.Y., Jang,S., Ko,J.,
Park,S.J., Lim,S.G., Yoon,D., Yi,J., Lee,S., Kim,M.O., Choi,S.K.
and Ryoo,Z.Y.
TITLE JAZF1 heterozygous knockout mice show altered adipose development
and metabolism
JOURNAL Cell Biosci 11 (1), 161 (2021)
PUBMED 34407873
REMARK Publication Status: Online-Only
REFERENCE 5 (residues 1 to 243)
AUTHORS Bedogni,F. and Hevner,R.F.
TITLE Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
Intermediate Progenitors Implicated in Axon Development
JOURNAL Front Mol Neurosci 14, 686034 (2021)
PUBMED 34321999
REMARK Publication Status: Online-Only
REFERENCE 6 (residues 1 to 243)
AUTHORS Li,L., Yang,Y., Yang,G., Lu,C., Yang,M., Liu,H. and Zong,H.
TITLE The role of JAZF1 on lipid metabolism and related genes in vitro
JOURNAL Metabolism 60 (4), 523-530 (2011)
PUBMED 20580384
REMARK GeneRIF: These results showed that JAZF1 in adipocytes and liver
cells reduces lipid synthesis and increases lipolysis
REFERENCE 7 (residues 1 to 243)
AUTHORS Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
Robson,P.
TITLE Resolution of cell fate decisions revealed by single-cell gene
expression analysis from zygote to blastocyst
JOURNAL Dev Cell 18 (4), 675-685 (2010)
PUBMED 20412781
REFERENCE 8 (residues 1 to 243)
AUTHORS Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
TITLE A systems approach reveals that the myogenesis genome network is
regulated by the transcriptional repressor RP58
JOURNAL Dev Cell 17 (6), 836-848 (2009)
PUBMED 20059953
REFERENCE 9 (residues 1 to 243)
AUTHORS Lehoczky,J.A., Williams,M.E. and Innis,J.W.
TITLE Conserved expression domains for genes upstream and within the HoxA
and HoxD clusters suggests a long-range enhancer existed before
cluster duplication
JOURNAL Evol Dev 6 (6), 423-430 (2004)
PUBMED 15509224
REFERENCE 10 (residues 1 to 243)
AUTHORS Nakajima,T., Fujino,S., Nakanishi,G., Kim,Y.S. and Jetten,A.M.
TITLE TIP27: a novel repressor of the nuclear orphan receptor TAK1/TR4
JOURNAL Nucleic Acids Res 32 (14), 4194-4204 (2004)
PUBMED 15302918
REMARK Publication Status: Online-Only
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AC084326.5, AC107317.3 and AC117212.5.
On Nov 26, 2009 this sequence version replaced NP_775582.1.
Transcript Variant: This variant (1) encodes the longest isoform
(1).
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AK050474.1, SRR17784643.631120.1
[ECO:0000332]
RNAseq introns :: mixed sample support SAMN00849374,
SAMN00849375 [ECO:0006172]
##Evidence-Data-END##
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on conservation, expression,
longest protein
##RefSeq-Attributes-END##
FEATURES Location/Qualifiers
source 1..243
/organism="Mus musculus"
/strain="C57BL/6"
/db_xref="taxon:10090"
/chromosome="6"
/map="6 25.74 cM"
Protein 1..243
/product="juxtaposed with another zinc finger protein 1
isoform 1"
/note="juxtaposed with another zinc finger protein 1"
/calculated_mol_wt=26966
Region 39..79
/region_name="Required for interaction with NR2C2.
/evidence=ECO:0000250|UniProtKB:Q86VZ6"
/note="propagated from UniProtKB/Swiss-Prot (Q80ZQ5.2)"
Region 89..151
/region_name="Disordered.
/evidence=ECO:0000256|SAM:MobiDB-lite"
/note="propagated from UniProtKB/Swiss-Prot (Q80ZQ5.2)"
Site 109
/site_type="phosphorylation"
/note="Phosphothreonine.
/evidence=ECO:0007744|PubMed:21183079; propagated from
UniProtKB/Swiss-Prot (Q80ZQ5.2)"
Site 113
/site_type="phosphorylation"
/note="Phosphothreonine.
/evidence=ECO:0007744|PubMed:21183079; propagated from
UniProtKB/Swiss-Prot (Q80ZQ5.2)"
Region <169..230
/region_name="SFP1"
/note="Putative transcriptional repressor regulating G2/M
transition [Transcription / Cell division and chromosome
partitioning]; COG5189"
/db_xref="CDD:227516"
CDS 1..243
/gene="Jazf1"
/gene_synonym="C820002C15; Jaz1; Tip27"
/coded_by="NM_173406.4:62..793"
/note="isoform 1 is encoded by transcript variant 1"
/db_xref="CCDS:CCDS20152.1"
/db_xref="GeneID:231986"
/db_xref="MGI:MGI:2141450"
ORIGIN
1 mtgiaaasff sntcrfggcg lhfptladli ehiednhidt dprvlekqel qqptyvalsy
61 inrfmtdaar reqeslkkki qpklsltlss svsrgnvstp prhssgsltp pvtppitpss
121 sfrsstptgs eydeeevdye esdsdeswtt esaisseail ssmcmnggee kpfacpvpgc
181 kkryknvngi kyhaknghrt qirvrkpfkc rcgksyktaq glrhhtinfh ppvsaemirk
241 mqq
//