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juxtaposed with another zinc finger protein 1 isoform 1 [Mus musculus]

NCBI Reference Sequence: NP_775582.2

Identical Proteins FASTA Graphics 

LOCUS       NP_775582                243 aa            linear   ROD 02-MAY-2024
DEFINITION  juxtaposed with another zinc finger protein 1 isoform 1 [Mus
            musculus].
ACCESSION   NP_775582
VERSION     NP_775582.2
DBSOURCE    REFSEQ: accession NM_173406.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 243)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 243)
  AUTHORS   Lee,H.Y., Jang,H.R., Li,H., Samuel,V.T., Dudek,K.D.,
            Osipovich,A.B., Magnuson,M.A., Sklar,J. and Shulman,G.I.
  TITLE     Deletion of Jazf1 gene causes early growth retardation and insulin
            resistance in mice
  JOURNAL   Proc Natl Acad Sci U S A 119 (49), e2213628119 (2022)
   PUBMED   36442127
  REMARK    GeneRIF: Deletion of Jazf1 gene causes early growth retardation and
            insulin resistance in mice.
REFERENCE   3  (residues 1 to 243)
  AUTHORS   Wang,Q., Dong,Y. and Wang,H.
  TITLE     microRNA-19b-3p-containing extracellular vesicles derived from
            macrophages promote the development of atherosclerosis by targeting
            JAZF1
  JOURNAL   J Cell Mol Med 26 (1), 48-59 (2022)
   PUBMED   34910364
  REMARK    GeneRIF: microRNA-19b-3p-containing extracellular vesicles derived
            from macrophages promote the development of atherosclerosis by
            targeting JAZF1.
REFERENCE   4  (residues 1 to 243)
  AUTHORS   Jeong,J., Jang,S., Park,S., Kwon,W., Kim,S.Y., Jang,S., Ko,J.,
            Park,S.J., Lim,S.G., Yoon,D., Yi,J., Lee,S., Kim,M.O., Choi,S.K.
            and Ryoo,Z.Y.
  TITLE     JAZF1 heterozygous knockout mice show altered adipose development
            and metabolism
  JOURNAL   Cell Biosci 11 (1), 161 (2021)
   PUBMED   34407873
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 243)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 243)
  AUTHORS   Li,L., Yang,Y., Yang,G., Lu,C., Yang,M., Liu,H. and Zong,H.
  TITLE     The role of JAZF1 on lipid metabolism and related genes in vitro
  JOURNAL   Metabolism 60 (4), 523-530 (2011)
   PUBMED   20580384
  REMARK    GeneRIF: These results showed that JAZF1 in adipocytes and liver
            cells reduces lipid synthesis and increases lipolysis
REFERENCE   7  (residues 1 to 243)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   8  (residues 1 to 243)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   9  (residues 1 to 243)
  AUTHORS   Lehoczky,J.A., Williams,M.E. and Innis,J.W.
  TITLE     Conserved expression domains for genes upstream and within the HoxA
            and HoxD clusters suggests a long-range enhancer existed before
            cluster duplication
  JOURNAL   Evol Dev 6 (6), 423-430 (2004)
   PUBMED   15509224
REFERENCE   10 (residues 1 to 243)
  AUTHORS   Nakajima,T., Fujino,S., Nakanishi,G., Kim,Y.S. and Jetten,A.M.
  TITLE     TIP27: a novel repressor of the nuclear orphan receptor TAK1/TR4
  JOURNAL   Nucleic Acids Res 32 (14), 4194-4204 (2004)
   PUBMED   15302918
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC084326.5, AC107317.3 and AC117212.5.
            
            On Nov 26, 2009 this sequence version replaced NP_775582.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK050474.1, SRR17784643.631120.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..243
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 25.74 cM"
     Protein         1..243
                     /product="juxtaposed with another zinc finger protein 1
                     isoform 1"
                     /note="juxtaposed with another zinc finger protein 1"
                     /calculated_mol_wt=26966
     Region          39..79
                     /region_name="Required for interaction with NR2C2.
                     /evidence=ECO:0000250|UniProtKB:Q86VZ6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q80ZQ5.2)"
     Region          89..151
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q80ZQ5.2)"
     Site            109
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q80ZQ5.2)"
     Site            113
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q80ZQ5.2)"
     Region          <169..230
                     /region_name="SFP1"
                     /note="Putative transcriptional repressor regulating G2/M
                     transition [Transcription / Cell division and chromosome
                     partitioning]; COG5189"
                     /db_xref="CDD:227516"
     CDS             1..243
                     /gene="Jazf1"
                     /gene_synonym="C820002C15; Jaz1; Tip27"
                     /coded_by="NM_173406.4:62..793"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS20152.1"
                     /db_xref="GeneID:231986"
                     /db_xref="MGI:MGI:2141450"
ORIGIN      
        1 mtgiaaasff sntcrfggcg lhfptladli ehiednhidt dprvlekqel qqptyvalsy
       61 inrfmtdaar reqeslkkki qpklsltlss svsrgnvstp prhssgsltp pvtppitpss
      121 sfrsstptgs eydeeevdye esdsdeswtt esaisseail ssmcmnggee kpfacpvpgc
      181 kkryknvngi kyhaknghrt qirvrkpfkc rcgksyktaq glrhhtinfh ppvsaemirk
      241 mqq
//
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