signal peptide peptidase-like 2B isoform 1 precursor [Mus musculus]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

The intramembrane proteases SPPL2a and SPPL2b regulate the homeostasis of selected SNARE proteins. [FEBS J. 2023]
The intramembrane proteases SPPL2a and SPPL2b regulate the homeostasis of selected SNARE proteins.
Ballin M, Griep W, Patel M, Karl M, Mentrup T, Rivera-Monroy J, Foo B, Schwappach B, Schröder B. FEBS J. 2023 May; 290(9):2320-2337. Epub 2022 Sep 13.
The intramembrane proteases signal Peptide peptidase-like 2a and 2b have distinct functions in vivo. [Mol Cell Biol. 2014]
The intramembrane proteases signal Peptide peptidase-like 2a and 2b have distinct functions in vivo.
Schneppenheim J, Hüttl S, Mentrup T, Lüllmann-Rauch R, Rothaug M, Engelke M, Dittmann K, Dressel R, Araki M, Araki K, et al. Mol Cell Biol. 2014 Apr; 34(8):1398-411. Epub 2014 Feb 3.
Signal peptide peptidase-like 2b modulates the amyloidogenic pathway and exhibits an Aβ-dependent expression in Alzheimer's disease. [Prog Neurobiol. 2024]
Signal peptide peptidase-like 2b modulates the amyloidogenic pathway and exhibits an Aβ-dependent expression in Alzheimer's disease.
Maccioni R, Travisan C, Badman J, Zerial S, Wagener A, Andrade-Talavera Y, Picciau F, Grassi C, Chen G, Lemoine L, et al. Prog Neurobiol. 2024 Apr; 235:102585. Epub 2024 Feb 15.

RefSeq mRNA
See reference mRNA sequence for the Sppl2b gene (NM_175195.3).
RefSeq protein isoforms
See 17 reference sequence protein isoforms for the Sppl2b gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CCDS
Link to Consensus CDS
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
HomoloGene
Related HomoloGene
Protein (UniProtKB)
Protein gi (refseq) to protein gi (UniProtKB)
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Ensembl [Ensembl]
Ensembl
Ensembl [Ensembl]
Ensembl
Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

Your browsing activity is empty.

Activity recording is turned off.

Protein