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pancreatic progenitor cell differentiation and proliferation factor B [Danio rerio]

NCBI Reference Sequence: NP_956302.1

Identical Proteins FASTA Graphics 

LOCUS       NP_956302                115 aa            linear   VRT 16-SEP-2024
DEFINITION  pancreatic progenitor cell differentiation and proliferation factor
            B [Danio rerio].
ACCESSION   NP_956302
VERSION     NP_956302.1
DBSOURCE    REFSEQ: accession NM_200008.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 115)
  AUTHORS   Carril Pardo,C.A., Massoz,L., Dupont,M.A., Bergemann,D.,
            Bourdouxhe,J., Lavergne,A., Tarifeno-Saldivia,E., Helker,C.S.,
            Stainier,D.Y., Peers,B., Voz,M.M. and Manfroid,I.
  TITLE     A delta-cell subpopulation with a pro-beta-cell identity
            contributes to efficient age-independent recovery in a zebrafish
            model of diabetes
  JOURNAL   Elife 11, e67576 (2022)
   PUBMED   35060900
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 115)
  AUTHORS   Singh,S.P., Chawla,P., Hnatiuk,A., Kamel,M., Silva,L.D.,
            Spanjaard,B., Eski,S.E., Janjuha,S., Olivares-Chauvet,P.,
            Kayisoglu,O., Rost,F., Blasche,J., Krankel,A., Petzold,A.,
            Kurth,T., Reinhardt,S., Junker,J.P. and Ninov,N.
  TITLE     A single-cell atlas of de novo beta-cell regeneration reveals the
            contribution of hybrid beta/delta-cells to diabetes recovery in
            zebrafish
  JOURNAL   Development 149 (2) (2022)
   PUBMED   35088828
REFERENCE   3  (residues 1 to 115)
  AUTHORS   Ben-Yair,R., Butty,V.L., Busby,M., Qiu,Y., Levine,S.S., Goren,A.,
            Boyer,L.A., Burns,C.G. and Burns,C.E.
  TITLE     H3K27me3-mediated silencing of structural genes is required for
            zebrafish heart regeneration
  JOURNAL   Development 146 (19) (2019)
   PUBMED   31427288
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 115)
  AUTHORS   Tarifeno-Saldivia,E., Lavergne,A., Bernard,A., Padamata,K.,
            Bergemann,D., Voz,M.L., Manfroid,I. and Peers,B.
  TITLE     Transcriptome analysis of pancreatic cells across distant species
            highlights novel important regulator genes
  JOURNAL   BMC Biol 15 (1), 21 (2017)
   PUBMED   28327131
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 115)
  AUTHORS   Bayes,A., Collins,M.O., Reig-Viader,R., Gou,G., Goulding,D.,
            Izquierdo,A., Choudhary,J.S., Emes,R.D. and Grant,S.G.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 115)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   7  (residues 1 to 115)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   8  (residues 1 to 115)
  AUTHORS   Rosel,T.D., Hung,L.H., Medenbach,J., Donde,K., Starke,S., Benes,V.,
            Ratsch,G. and Bindereif,A.
  TITLE     RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in
            alternative splicing regulation
  JOURNAL   EMBO J 30 (10), 1965-1976 (2011)
   PUBMED   21468032
REFERENCE   9  (residues 1 to 115)
  AUTHORS   Jiang,Z., Song,J., Qi,F., Xiao,A., An,X., Liu,N.A., Zhu,Z.,
            Zhang,B. and Lin,S.
  TITLE     Exdpf is a key regulator of exocrine pancreas development
            controlled by retinoic acid and ptf1a in zebrafish
  JOURNAL   PLoS Biol 6 (11), e293 (2008)
   PUBMED   19067490
REFERENCE   10 (residues 1 to 115)
  AUTHORS   Woods,I.G., Wilson,C., Friedlander,B., Chang,P., Reyes,D.K.,
            Nix,R., Kelly,P.D., Chu,F., Postlethwait,J.H. and Talbot,W.S.
  TITLE     The zebrafish gene map defines ancestral vertebrate chromosomes
  JOURNAL   Genome Res 15 (9), 1307-1314 (2005)
   PUBMED   16109975
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC059699.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CO913873.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA4476732, SAMEA4476735
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..115
                     /organism="Danio rerio"
                     /strain="wild type"
                     /db_xref="taxon:7955"
                     /chromosome="23"
                     /map="23"
     Protein         1..115
                     /product="pancreatic progenitor cell differentiation and
                     proliferation factor B"
                     /note="exocrine differentiation and proliferation factor
                     B; chromosome 20 open reading frame 149, like; endpf;
                     endocrine differentiation and proliferation factor"
                     /calculated_mol_wt=11953
     Region          1..106
                     /region_name="PPDFL"
                     /note="Differentiation and proliferation regulator;
                     pfam15060"
                     /db_xref="CDD:464477"
     Region          21..48
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6PBI2.1)"
     CDS             1..115
                     /gene="ppdpfb"
                     /gene_synonym="c20orf149b; c20orf149l; wu:fj62f01;
                     zgc:73395"
                     /coded_by="NM_200008.1:166..513"
                     /db_xref="GeneID:336303"
                     /db_xref="ZFIN:ZDB-GENE-030131-8247"
ORIGIN      
        1 maaipasgsl vathdyyrrr igstsssssc gsseysgevi phhpglpkqd sghwwssfff
       61 gkqnlpgmgt vaeeaqqksg vvsvtngqvt cvaremvmrq asessdggks eagns
//
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Reference sequence information

  • RefSeq mRNA
    See reference mRNA sequence for the ppdpfb gene (NM_200008.1).

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