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membrane-spanning 4-domains subfamily A member 10 [Homo sapiens]

NCBI Reference Sequence: NP_996776.2

Identical Proteins FASTA Graphics 

LOCUS       NP_996776                267 aa            linear   PRI 20-SEP-2024
DEFINITION  membrane-spanning 4-domains subfamily A member 10 [Homo sapiens].
ACCESSION   NP_996776 XP_291890
VERSION     NP_996776.2
DBSOURCE    REFSEQ: accession NM_206893.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 267)
  AUTHORS   Benz,C., Ali,M., Krystkowiak,I., Simonetti,L., Sayadi,A.,
            Mihalic,F., Kliche,J., Andersson,E., Jemth,P., Davey,N.E. and
            Ivarsson,Y.
  TITLE     Proteome-scale mapping of binding sites in the unstructured regions
            of the human proteome
  JOURNAL   Mol Syst Biol 18 (1), e10584 (2022)
   PUBMED   35044719
REFERENCE   2  (residues 1 to 267)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (residues 1 to 267)
  AUTHORS   Liang,Y., Buckley,T.R., Tu,L., Langdon,S.D. and Tedder,T.F.
  TITLE     Structural organization of the human MS4A gene cluster on
            Chromosome 11q12
  JOURNAL   Immunogenetics 53 (5), 357-368 (2001)
   PUBMED   11486273
REFERENCE   4  (residues 1 to 267)
  AUTHORS   Liang,Y. and Tedder,T.F.
  TITLE     Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene
            family: sixteen new MS4A family members expressed in human and
            mouse
  JOURNAL   Genomics 72 (2), 119-127 (2001)
   PUBMED   11401424
REFERENCE   5  (residues 1 to 267)
  AUTHORS   Ishibashi,K., Suzuki,M., Sasaki,S. and Imai,M.
  TITLE     Identification of a new multigene four-transmembrane family (MS4A)
            related to CD20, HTm4 and beta subunit of the high-affinity IgE
            receptor
  JOURNAL   Gene 264 (1), 87-93 (2001)
   PUBMED   11245982
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP004243.2 and AK122633.1.
            
            On Feb 8, 2008 this sequence version replaced NP_996776.1.
            
            Summary: Most MS4A genes, including MS4A10, encode proteins with at
            least 4 potential transmembrane domains and N- and C-terminal
            cytoplasmic domains encoded by distinct exons.[supplied by OMIM,
            Apr 2004].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because transcript sequence consistent with
            the reference genome assembly was not available for all regions of
            the RefSeq transcript. The extent of this transcript is supported
            by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK122633.1, BC137259.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2144835, SAMEA2152474
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000308287.2/ ENSP00000311862.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.2"
     Protein         1..267
                     /product="membrane-spanning 4-domains subfamily A member
                     10"
                     /note="CD20 antigen-like 7; membrane-spanning 4-domains,
                     subfamily A, member 10"
                     /calculated_mol_wt=29616
     Region          60..193
                     /region_name="CD20"
                     /note="CD20-like family; pfam04103"
                     /db_xref="CDD:461174"
     Site            62..82
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q96PG2.3)"
     Site            92..112
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q96PG2.3)"
     Site            122..142
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q96PG2.3)"
     Site            172..192
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q96PG2.3)"
     CDS             1..267
                     /gene="MS4A10"
                     /gene_synonym="CD20L7; MS4A9"
                     /coded_by="NM_206893.4:112..915"
                     /db_xref="CCDS:CCDS7992.1"
                     /db_xref="GeneID:341116"
                     /db_xref="HGNC:HGNC:13368"
                     /db_xref="MIM:608403"
ORIGIN      
        1 mkaeatvips rcarglpswq vlspvqpwqt sapqnttqpk llaphqheks qkkssllkel
       61 gafhitiall hlvfggylas ivknlhlvvl kswypfwgaa sflisgilai tmktfsktyl
      121 kmlclmtnli slfcvlsglf viskdlfles pfespiwrmy pnstvhiqrl elallcftvl
      181 elflpvptav tawrgdcpsa knddaclvpn tplhlkglpv epppsyqsvi qgdaqhkqhq
      241 rlrevkqvap dtwivtdgaa iwtqtan
//
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