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ubiquitin carboxyl-terminal hydrolase 33 [Danio rerio]

NCBI Reference Sequence: NP_998392.1

Identical Proteins FASTA Graphics 

LOCUS       NP_998392                897 aa            linear   VRT 16-SEP-2024
DEFINITION  ubiquitin carboxyl-terminal hydrolase 33 [Danio rerio].
ACCESSION   NP_998392
VERSION     NP_998392.1
DBSOURCE    REFSEQ: accession NM_213227.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 897)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 897)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 897)
  AUTHORS   Kok,F.O., Shin,M., Ni,C.W., Gupta,A., Grosse,A.S., van Impel,A.,
            Kirchmaier,B.C., Peterson-Maduro,J., Kourkoulis,G., Male,I.,
            DeSantis,D.F., Sheppard-Tindell,S., Ebarasi,L., Betsholtz,C.,
            Schulte-Merker,S., Wolfe,S.A. and Lawson,N.D.
  TITLE     Reverse genetic screening reveals poor correlation between
            morpholino-induced and mutant phenotypes in zebrafish
  JOURNAL   Dev Cell 32 (1), 97-108 (2015)
   PUBMED   25533206
REFERENCE   4  (residues 1 to 897)
  AUTHORS   Tse,W.K., Eisenhaber,B., Ho,S.H., Ng,Q., Eisenhaber,F. and
            Jiang,Y.J.
  TITLE     Genome-wide loss-of-function analysis of deubiquitylating enzymes
            for zebrafish development
  JOURNAL   BMC Genomics 10, 637 (2009)
   PUBMED   20040115
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC066557.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC066557.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505370, SAMEA3505373
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..897
                     /organism="Danio rerio"
                     /db_xref="taxon:7955"
                     /chromosome="2"
                     /map="2"
     Protein         1..897
                     /product="ubiquitin carboxyl-terminal hydrolase 33"
                     /EC_number="3.4.19.12"
                     /note="deubiquitinating enzyme 33; ubiquitin thiolesterase
                     33; ubiquitin-specific-processing protease 33; ubiquitin
                     thioesterase 33"
                     /calculated_mol_wt=100557
     Region          31..91
                     /region_name="zf-UBP"
                     /note="Zn-finger in ubiquitin-hydrolases and other
                     protein; pfam02148"
                     /db_xref="CDD:460464"
     Region          156..667
                     /region_name="UCH"
                     /note="Ubiquitin carboxyl-terminal hydrolase; pfam00443"
                     /db_xref="CDD:425685"
     Region          261..308
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (A5PMR2.1)"
     Region          343..420
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (A5PMR2.1)"
     Region          687..769
                     /region_name="DUSP"
                     /note="Domain in ubiquitin-specific proteases; smart00695"
                     /db_xref="CDD:197831"
     Region          795..879
                     /region_name="DUSP"
                     /note="Domain in ubiquitin-specific proteases; smart00695"
                     /db_xref="CDD:197831"
     Region          875..897
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (A5PMR2.1)"
     CDS             1..897
                     /gene="usp33"
                     /gene_synonym="zgc:77308"
                     /coded_by="NM_213227.1:194..2887"
                     /db_xref="GeneID:406508"
                     /db_xref="ZFIN:ZDB-GENE-040426-2323"
ORIGIN      
        1 msgvssndcp hlecvgeitk eeliqkshgq cqdckvggpn lwaclengcs yvgcgeshad
       61 hstvhsqetr hnltvnlttl rvwcyactke vflerklgph kqlpnaakav spvqtpcqdl
      121 ntpgsptslr vpsagtcddl dmeteeedel rtrgltglkn igntcymnaa lqalsncppl
      181 tqfflecggl vktdkkpalc ksyqklvtdl whknrnsyvv ptnlfqgika vnpmfrgysq
      241 qdsqeflrcl mdqlheelke lipepedpnq avamddspde dnhsqsddfq scescgssdr
      301 adnegprvpe dineaemlmp eqnqnnrdwq keknlinnly ragshgdldk dvdttsdsrp
      361 iissqgaika qgrtsdseiq vsstvrpqsp tgnegitsrl sssppkssaw pnlssthkkv
      421 pmftptktkr qrkyhsiise vfdgtivssv qcltcdrvsv tlenfqdisl pipgkedlak
      481 lhssshqtal vkagscgeay apqgwiafvm eyikswfwgp vvtlqdclaa ffardelkgd
      541 nmyscekckk lrngvkfckv qslpeilcih lkrfrhelmf stkigthvsf pleglemqpf
      601 lakdssaltt tydllsvich hgtassghyi aycrnelnql wyefddqsvt evsescvqna
      661 eayvlfykks ndetqkerrk vtslfnmmep sllqfyvsrq wlnkfktfae pgpisnhdfl
      721 cahggippnk atyiddlvlm ipqnvwdhly srygggpavn hlyvchtcqn eieklekrrk
      781 neldmfvrln kafqeeespv viycismqwf rewesfvkgk didppgpidn skiavnkngh
      841 itlkpgadsg qiseetwnfl hnihgggpvv tvrpsvshqe setsqseeki evetrtv
//
Feature
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Reference sequence information

  • RefSeq mRNA
    See reference mRNA sequence for the usp33 gene (NM_213227.1).

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