LOCUS NP_998392 897 aa linear VRT 16-SEP-2024
DEFINITION ubiquitin carboxyl-terminal hydrolase 33 [Danio rerio].
ACCESSION NP_998392
VERSION NP_998392.1
DBSOURCE REFSEQ: accession NM_213227.1
KEYWORDS RefSeq.
SOURCE Danio rerio (zebrafish)
ORGANISM Danio rerio
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE 1 (residues 1 to 897)
AUTHORS Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
Guiguen,Y. and Bobe,J.
TITLE Gene evolution and gene expression after whole genome duplication
in fish: the PhyloFish database
JOURNAL BMC Genomics 17, 368 (2016)
PUBMED 27189481
REMARK Publication Status: Online-Only
REFERENCE 2 (residues 1 to 897)
AUTHORS Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
TITLE RFX transcription factors are essential for hearing in mice
JOURNAL Nat Commun 6, 8549 (2015)
PUBMED 26469318
REMARK Publication Status: Online-Only
REFERENCE 3 (residues 1 to 897)
AUTHORS Kok,F.O., Shin,M., Ni,C.W., Gupta,A., Grosse,A.S., van Impel,A.,
Kirchmaier,B.C., Peterson-Maduro,J., Kourkoulis,G., Male,I.,
DeSantis,D.F., Sheppard-Tindell,S., Ebarasi,L., Betsholtz,C.,
Schulte-Merker,S., Wolfe,S.A. and Lawson,N.D.
TITLE Reverse genetic screening reveals poor correlation between
morpholino-induced and mutant phenotypes in zebrafish
JOURNAL Dev Cell 32 (1), 97-108 (2015)
PUBMED 25533206
REFERENCE 4 (residues 1 to 897)
AUTHORS Tse,W.K., Eisenhaber,B., Ho,S.H., Ng,Q., Eisenhaber,F. and
Jiang,Y.J.
TITLE Genome-wide loss-of-function analysis of deubiquitylating enzymes
for zebrafish development
JOURNAL BMC Genomics 10, 637 (2009)
PUBMED 20040115
REMARK Publication Status: Online-Only
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from BC066557.1.
##Evidence-Data-START##
Transcript exon combination :: BC066557.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMEA3505370, SAMEA3505373
[ECO:0000348]
##Evidence-Data-END##
FEATURES Location/Qualifiers
source 1..897
/organism="Danio rerio"
/db_xref="taxon:7955"
/chromosome="2"
/map="2"
Protein 1..897
/product="ubiquitin carboxyl-terminal hydrolase 33"
/EC_number="3.4.19.12"
/note="deubiquitinating enzyme 33; ubiquitin thiolesterase
33; ubiquitin-specific-processing protease 33; ubiquitin
thioesterase 33"
/calculated_mol_wt=100557
Region 31..91
/region_name="zf-UBP"
/note="Zn-finger in ubiquitin-hydrolases and other
protein; pfam02148"
/db_xref="CDD:460464"
Region 156..667
/region_name="UCH"
/note="Ubiquitin carboxyl-terminal hydrolase; pfam00443"
/db_xref="CDD:425685"
Region 261..308
/region_name="Disordered.
/evidence=ECO:0000256|SAM:MobiDB-lite"
/note="propagated from UniProtKB/Swiss-Prot (A5PMR2.1)"
Region 343..420
/region_name="Disordered.
/evidence=ECO:0000256|SAM:MobiDB-lite"
/note="propagated from UniProtKB/Swiss-Prot (A5PMR2.1)"
Region 687..769
/region_name="DUSP"
/note="Domain in ubiquitin-specific proteases; smart00695"
/db_xref="CDD:197831"
Region 795..879
/region_name="DUSP"
/note="Domain in ubiquitin-specific proteases; smart00695"
/db_xref="CDD:197831"
Region 875..897
/region_name="Disordered.
/evidence=ECO:0000256|SAM:MobiDB-lite"
/note="propagated from UniProtKB/Swiss-Prot (A5PMR2.1)"
CDS 1..897
/gene="usp33"
/gene_synonym="zgc:77308"
/coded_by="NM_213227.1:194..2887"
/db_xref="GeneID:406508"
/db_xref="ZFIN:ZDB-GENE-040426-2323"
ORIGIN
1 msgvssndcp hlecvgeitk eeliqkshgq cqdckvggpn lwaclengcs yvgcgeshad
61 hstvhsqetr hnltvnlttl rvwcyactke vflerklgph kqlpnaakav spvqtpcqdl
121 ntpgsptslr vpsagtcddl dmeteeedel rtrgltglkn igntcymnaa lqalsncppl
181 tqfflecggl vktdkkpalc ksyqklvtdl whknrnsyvv ptnlfqgika vnpmfrgysq
241 qdsqeflrcl mdqlheelke lipepedpnq avamddspde dnhsqsddfq scescgssdr
301 adnegprvpe dineaemlmp eqnqnnrdwq keknlinnly ragshgdldk dvdttsdsrp
361 iissqgaika qgrtsdseiq vsstvrpqsp tgnegitsrl sssppkssaw pnlssthkkv
421 pmftptktkr qrkyhsiise vfdgtivssv qcltcdrvsv tlenfqdisl pipgkedlak
481 lhssshqtal vkagscgeay apqgwiafvm eyikswfwgp vvtlqdclaa ffardelkgd
541 nmyscekckk lrngvkfckv qslpeilcih lkrfrhelmf stkigthvsf pleglemqpf
601 lakdssaltt tydllsvich hgtassghyi aycrnelnql wyefddqsvt evsescvqna
661 eayvlfykks ndetqkerrk vtslfnmmep sllqfyvsrq wlnkfktfae pgpisnhdfl
721 cahggippnk atyiddlvlm ipqnvwdhly srygggpavn hlyvchtcqn eieklekrrk
781 neldmfvrln kafqeeespv viycismqwf rewesfvkgk didppgpidn skiavnkngh
841 itlkpgadsg qiseetwnfl hnihgggpvv tvrpsvshqe setsqseeki evetrtv
//