RecName: Full=Serine/threonine-protein phosphatase 6 catalytic subunit - Protein

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PP6 negatively modulates LUBAC-mediated M1-ubiquitination of RIPK1 and c-FLIP(L) to promote TNFα-mediated cell death. [Cell Death Dis. 2022]
PP6 negatively modulates LUBAC-mediated M1-ubiquitination of RIPK1 and c-FLIP(L) to promote TNFα-mediated cell death.
Wu G, Li D, Liang W, Sun W, Xie X, Tong Y, Shan B, Zhang M, Lu X, Yuan J, et al. Cell Death Dis. 2022 Sep 7; 13(9):773. Epub 2022 Sep 7.
Protein phosphatase 6 promotes neurite outgrowth by promoting mTORC2 activity in N2a cells. [J Biochem. 2021]
Protein phosphatase 6 promotes neurite outgrowth by promoting mTORC2 activity in N2a cells.
Kitamura N, Fujiwara N, Hayakawa K, Ohama T, Sato K. J Biochem. 2021 Sep 22; 170(1):131-138.
PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK. [Cell Rep. 2021]
PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK.
Cho E, Lou HJ, Kuruvilla L, Calderwood DA, Turk BE. Cell Rep. 2021 Mar 30; 34(13):108928.

RefSeq protein isoforms
See 11 reference sequence protein isoforms for the PPP6C gene.

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O00743 [Domain Mapping of Disease Mut...]
O00743
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
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Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
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ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

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Protein